Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 344151..344802 Replicon plasmid unnamed1
Accession NZ_CP040096
Organism Pantoea sp. SO10

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FCN45_RS21075 Protein ID WP_137387145.1
Coordinates 344458..344802 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FCN45_RS21070 Protein ID WP_137387144.1
Coordinates 344151..344465 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN45_RS21055 340052..340741 - 690 WP_137387141.1 aspartate/glutamate racemase family protein -
FCN45_RS21060 340757..342814 - 2058 WP_137387142.1 FUSC family protein -
FCN45_RS21065 343069..344016 + 948 WP_137387143.1 sulfonate ABC transporter substrate-binding protein -
FCN45_RS21070 344151..344465 - 315 WP_137387144.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FCN45_RS21075 344458..344802 - 345 WP_137387145.1 toxin Toxin
FCN45_RS21080 345284..346498 - 1215 WP_137387146.1 acyl-CoA dehydrogenase family protein -
FCN45_RS21085 346495..347934 - 1440 WP_137387147.1 MFS transporter -
FCN45_RS21090 348112..348987 - 876 WP_101761172.1 metal ABC transporter substrate-binding protein -
FCN45_RS21095 348984..349682 - 699 WP_137387148.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..744154 744154


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-88)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13492.32 Da        Isoelectric Point: 9.9070

>T124939 WP_137387145.1 NZ_CP040096:c344802-344458 [Pantoea sp. SO10]
MHATFIELSSFQKYRVEYLSDDQFRLFQNMLMADPEKGDVIPDTGGLRKVRFRDERRNKGTRGGIRVIYYWTNEKGQFIL
FTIYDKDQRDDLTKQQRDALGSALNVIKKGLRHD

Download         Length: 345 bp

>T124939 NZ_CP040096:c344802-344458 [Pantoea sp. SO10]
ATGCACGCGACATTTATTGAGCTGTCCAGCTTTCAGAAGTACCGGGTGGAATACCTGAGCGATGATCAGTTTAGGCTTTT
CCAGAATATGTTGATGGCCGACCCTGAAAAGGGCGACGTGATCCCAGATACGGGCGGCCTGCGTAAAGTCCGGTTCAGGG
ATGAGCGTCGAAACAAGGGCACAAGAGGCGGCATTAGGGTTATCTATTACTGGACGAACGAAAAAGGCCAGTTCATCCTG
TTTACCATTTACGATAAGGATCAACGCGACGATCTGACCAAACAGCAGCGCGACGCCTTGGGTTCGGCGCTGAACGTGAT
TAAAAAGGGGCTGAGACATGACTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12024.77 Da        Isoelectric Point: 9.5358

>AT124939 WP_137387144.1 NZ_CP040096:c344465-344151 [Pantoea sp. SO10]
MTERDIFSELMTGMQELKDHKDGKITLKTYQVSKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRSRP
NAQAVLLIRMVQQNPETLKTLAQL

Download         Length: 315 bp

>AT124939 NZ_CP040096:c344465-344151 [Pantoea sp. SO10]
ATGACTGAACGCGATATTTTCAGTGAGCTGATGACGGGAATGCAGGAGCTGAAAGATCATAAGGACGGAAAAATCACGCT
CAAGACCTACCAGGTCAGCAAGCGCGCGCCCGTCACCATCGCGCCACAGGAGCTGCGTGATGTACGCGAAAAACTTAACC
TTTCTCAGGCCGTTTTTGCGCACTACCTTCACACAGGTGAAACCACCTATCAAAACTGGGAGCAAGGCAGGTCCAGGCCT
AACGCCCAGGCTGTTTTGCTTATACGCATGGTTCAGCAGAATCCTGAAACCCTGAAAACGCTCGCACAGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References