Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 1968276..1968927 | Replicon | chromosome |
Accession | NZ_CP040095 | ||
Organism | Pantoea sp. SO10 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | FCN45_RS09190 | Protein ID | WP_137385729.1 |
Coordinates | 1968577..1968927 (-) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | FCN45_RS09185 | Protein ID | WP_137385728.1 |
Coordinates | 1968276..1968575 (-) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FCN45_RS09165 | 1963803..1964558 | + | 756 | WP_137385725.1 | pyrroloquinoline-quinone synthase PqqC | - |
FCN45_RS09170 | 1964563..1964841 | + | 279 | WP_061720121.1 | pyrroloquinoline quinone biosynthesis peptide chaperone PqqD | - |
FCN45_RS09175 | 1964828..1965967 | + | 1140 | WP_137385726.1 | pyrroloquinoline quinone biosynthesis protein PqqE | - |
FCN45_RS09180 | 1965967..1968285 | + | 2319 | WP_137385727.1 | pyrroloquinoline quinone biosynthesis protein PqqF | - |
FCN45_RS09185 | 1968276..1968575 | - | 300 | WP_137385728.1 | helix-turn-helix transcriptional regulator | Antitoxin |
FCN45_RS09190 | 1968577..1968927 | - | 351 | WP_137385729.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FCN45_RS09195 | 1969110..1970816 | - | 1707 | WP_137385730.1 | D-lactate dehydrogenase | - |
FCN45_RS09200 | 1971250..1972230 | + | 981 | WP_101764479.1 | 6-phosphofructokinase | - |
FCN45_RS09205 | 1972241..1972555 | + | 315 | WP_008110086.1 | PTS sugar transporter subunit IIB | - |
FCN45_RS09210 | 1972548..1973921 | + | 1374 | WP_008110085.1 | PTS sugar transporter subunit IIC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 13367.52 Da Isoelectric Point: 7.1349
>T124934 WP_137385729.1 NZ_CP040095:c1968927-1968577 [Pantoea sp. SO10]
MWEILTTDVFDQWFVAQSEALREDVLAAMTILEEMGPQLGRPYVDTLKGGEFPNLKELRVQHAGKPIRAFFAFDPVRRAI
VLCAGNKTGFNQKQFYRTMIRLAEVEYCKHLARMEG
MWEILTTDVFDQWFVAQSEALREDVLAAMTILEEMGPQLGRPYVDTLKGGEFPNLKELRVQHAGKPIRAFFAFDPVRRAI
VLCAGNKTGFNQKQFYRTMIRLAEVEYCKHLARMEG
Download Length: 351 bp
>T124934 NZ_CP040095:c1968927-1968577 [Pantoea sp. SO10]
ATGTGGGAAATATTAACAACGGATGTTTTTGATCAGTGGTTTGTGGCGCAAAGTGAAGCACTACGTGAAGACGTGTTAGC
GGCGATGACGATTTTAGAAGAGATGGGACCACAACTTGGCCGCCCCTATGTCGATACATTAAAGGGTGGCGAATTCCCTA
ATCTGAAAGAGCTGCGCGTTCAGCACGCCGGTAAGCCCATCAGAGCCTTTTTCGCTTTTGATCCGGTGCGACGCGCTATC
GTGTTATGCGCTGGAAATAAGACCGGTTTTAACCAAAAACAATTTTACCGAACGATGATTCGCCTCGCTGAAGTGGAATA
CTGCAAGCATTTGGCGCGGATGGAGGGATAA
ATGTGGGAAATATTAACAACGGATGTTTTTGATCAGTGGTTTGTGGCGCAAAGTGAAGCACTACGTGAAGACGTGTTAGC
GGCGATGACGATTTTAGAAGAGATGGGACCACAACTTGGCCGCCCCTATGTCGATACATTAAAGGGTGGCGAATTCCCTA
ATCTGAAAGAGCTGCGCGTTCAGCACGCCGGTAAGCCCATCAGAGCCTTTTTCGCTTTTGATCCGGTGCGACGCGCTATC
GTGTTATGCGCTGGAAATAAGACCGGTTTTAACCAAAAACAATTTTACCGAACGATGATTCGCCTCGCTGAAGTGGAATA
CTGCAAGCATTTGGCGCGGATGGAGGGATAA
Antitoxin
Download Length: 100 a.a. Molecular weight: 11027.80 Da Isoelectric Point: 9.8627
>AT124934 WP_137385728.1 NZ_CP040095:c1968575-1968276 [Pantoea sp. SO10]
MATLKELMQKQSPESQQRIAVKVEILRQEIALSQLREELNLSQTELARTIGVSQPTLAKMENPGNDPRLSTLKRYVAALG
GELRIDVTLPNGKTIAFQL
MATLKELMQKQSPESQQRIAVKVEILRQEIALSQLREELNLSQTELARTIGVSQPTLAKMENPGNDPRLSTLKRYVAALG
GELRIDVTLPNGKTIAFQL
Download Length: 300 bp
>AT124934 NZ_CP040095:c1968575-1968276 [Pantoea sp. SO10]
ATGGCTACTCTGAAAGAATTAATGCAAAAACAATCACCTGAAAGCCAGCAGCGCATCGCTGTGAAAGTCGAAATATTGCG
CCAGGAGATTGCTTTAAGCCAGTTACGCGAAGAGCTCAACCTTTCGCAAACCGAACTGGCACGCACTATCGGCGTCTCGC
AGCCCACGCTGGCAAAGATGGAAAATCCAGGCAACGATCCGCGCCTGTCCACATTGAAACGTTACGTCGCGGCATTGGGT
GGCGAACTTCGTATCGACGTGACACTGCCCAACGGCAAAACCATCGCCTTTCAGCTTTGA
ATGGCTACTCTGAAAGAATTAATGCAAAAACAATCACCTGAAAGCCAGCAGCGCATCGCTGTGAAAGTCGAAATATTGCG
CCAGGAGATTGCTTTAAGCCAGTTACGCGAAGAGCTCAACCTTTCGCAAACCGAACTGGCACGCACTATCGGCGTCTCGC
AGCCCACGCTGGCAAAGATGGAAAATCCAGGCAACGATCCGCGCCTGTCCACATTGAAACGTTACGTCGCGGCATTGGGT
GGCGAACTTCGTATCGACGTGACACTGCCCAACGGCAAAACCATCGCCTTTCAGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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