Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1968276..1968927 Replicon chromosome
Accession NZ_CP040095
Organism Pantoea sp. SO10

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FCN45_RS09190 Protein ID WP_137385729.1
Coordinates 1968577..1968927 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FCN45_RS09185 Protein ID WP_137385728.1
Coordinates 1968276..1968575 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN45_RS09165 1963803..1964558 + 756 WP_137385725.1 pyrroloquinoline-quinone synthase PqqC -
FCN45_RS09170 1964563..1964841 + 279 WP_061720121.1 pyrroloquinoline quinone biosynthesis peptide chaperone PqqD -
FCN45_RS09175 1964828..1965967 + 1140 WP_137385726.1 pyrroloquinoline quinone biosynthesis protein PqqE -
FCN45_RS09180 1965967..1968285 + 2319 WP_137385727.1 pyrroloquinoline quinone biosynthesis protein PqqF -
FCN45_RS09185 1968276..1968575 - 300 WP_137385728.1 helix-turn-helix transcriptional regulator Antitoxin
FCN45_RS09190 1968577..1968927 - 351 WP_137385729.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FCN45_RS09195 1969110..1970816 - 1707 WP_137385730.1 D-lactate dehydrogenase -
FCN45_RS09200 1971250..1972230 + 981 WP_101764479.1 6-phosphofructokinase -
FCN45_RS09205 1972241..1972555 + 315 WP_008110086.1 PTS sugar transporter subunit IIB -
FCN45_RS09210 1972548..1973921 + 1374 WP_008110085.1 PTS sugar transporter subunit IIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13367.52 Da        Isoelectric Point: 7.1349

>T124934 WP_137385729.1 NZ_CP040095:c1968927-1968577 [Pantoea sp. SO10]
MWEILTTDVFDQWFVAQSEALREDVLAAMTILEEMGPQLGRPYVDTLKGGEFPNLKELRVQHAGKPIRAFFAFDPVRRAI
VLCAGNKTGFNQKQFYRTMIRLAEVEYCKHLARMEG

Download         Length: 351 bp

>T124934 NZ_CP040095:c1968927-1968577 [Pantoea sp. SO10]
ATGTGGGAAATATTAACAACGGATGTTTTTGATCAGTGGTTTGTGGCGCAAAGTGAAGCACTACGTGAAGACGTGTTAGC
GGCGATGACGATTTTAGAAGAGATGGGACCACAACTTGGCCGCCCCTATGTCGATACATTAAAGGGTGGCGAATTCCCTA
ATCTGAAAGAGCTGCGCGTTCAGCACGCCGGTAAGCCCATCAGAGCCTTTTTCGCTTTTGATCCGGTGCGACGCGCTATC
GTGTTATGCGCTGGAAATAAGACCGGTTTTAACCAAAAACAATTTTACCGAACGATGATTCGCCTCGCTGAAGTGGAATA
CTGCAAGCATTTGGCGCGGATGGAGGGATAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11027.80 Da        Isoelectric Point: 9.8627

>AT124934 WP_137385728.1 NZ_CP040095:c1968575-1968276 [Pantoea sp. SO10]
MATLKELMQKQSPESQQRIAVKVEILRQEIALSQLREELNLSQTELARTIGVSQPTLAKMENPGNDPRLSTLKRYVAALG
GELRIDVTLPNGKTIAFQL

Download         Length: 300 bp

>AT124934 NZ_CP040095:c1968575-1968276 [Pantoea sp. SO10]
ATGGCTACTCTGAAAGAATTAATGCAAAAACAATCACCTGAAAGCCAGCAGCGCATCGCTGTGAAAGTCGAAATATTGCG
CCAGGAGATTGCTTTAAGCCAGTTACGCGAAGAGCTCAACCTTTCGCAAACCGAACTGGCACGCACTATCGGCGTCTCGC
AGCCCACGCTGGCAAAGATGGAAAATCCAGGCAACGATCCGCGCCTGTCCACATTGAAACGTTACGTCGCGGCATTGGGT
GGCGAACTTCGTATCGACGTGACACTGCCCAACGGCAAAACCATCGCCTTTCAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References