Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 763248..763766 Replicon chromosome
Accession NZ_CP040020
Organism Brevibacterium sp. CS2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FDF13_RS03310 Protein ID WP_101652830.1
Coordinates 763248..763505 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FDF13_RS03315 Protein ID WP_137318439.1
Coordinates 763509..763766 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FDF13_RS03295 759725..760975 - 1251 WP_137318436.1 glutaminase -
FDF13_RS03300 761331..762113 + 783 WP_137318437.1 SDR family oxidoreductase -
FDF13_RS03305 762115..763185 + 1071 WP_137318438.1 hypothetical protein -
FDF13_RS03310 763248..763505 - 258 WP_101652830.1 Txe/YoeB family addiction module toxin Toxin
FDF13_RS03315 763509..763766 - 258 WP_137318439.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FDF13_RS03320 763824..765008 - 1185 WP_175406843.1 glycosyltransferase -
FDF13_RS03325 765028..766254 - 1227 WP_137318441.1 hypothetical protein -
FDF13_RS03330 766383..767315 - 933 WP_175407016.1 hypothetical protein -
FDF13_RS03335 767457..768677 + 1221 WP_175406844.1 glycosyltransferase family 1 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10356.83 Da        Isoelectric Point: 8.8720

>T124754 WP_101652830.1 NZ_CP040020:c763505-763248 [Brevibacterium sp. CS2]
MLLVWDEGAWEDYLWWQAQDRKVLKRINRLIKEIERNGNEGIGKPEPLKHDFAGYWSRRITDEHRLVYKLARDEIRIAAC
RYHYG

Download         Length: 258 bp

>T124754 NZ_CP040020:c763505-763248 [Brevibacterium sp. CS2]
ATGCTTCTGGTGTGGGATGAAGGTGCATGGGAGGACTACCTGTGGTGGCAGGCACAGGACCGAAAGGTACTCAAACGCAT
CAATCGCCTGATCAAGGAGATCGAGCGCAACGGCAACGAGGGGATCGGTAAACCGGAACCCCTCAAACACGATTTCGCAG
GATACTGGTCCCGGCGCATCACCGATGAGCATCGACTCGTCTACAAACTCGCTCGCGATGAGATCCGCATCGCAGCCTGT
CGATATCACTACGGATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9626.79 Da        Isoelectric Point: 4.6533

>AT124754 WP_137318439.1 NZ_CP040020:c763766-763509 [Brevibacterium sp. CS2]
MKTMSYTDSRANYAKVLDDVTNDREAVVITRAGHEPVVIVSLADYESLRETAYLMRSPANARRLLDAMERLEADRGQAHE
LIETD

Download         Length: 258 bp

>AT124754 NZ_CP040020:c763766-763509 [Brevibacterium sp. CS2]
ATGAAGACGATGAGCTACACAGATTCACGGGCCAATTATGCGAAAGTGCTCGACGATGTCACCAATGATCGGGAGGCGGT
CGTCATCACGCGCGCCGGCCATGAGCCGGTCGTCATTGTTTCCTTGGCGGATTACGAATCGCTTCGCGAAACCGCCTATC
TCATGCGATCGCCGGCCAACGCCCGTCGACTGCTGGATGCAATGGAACGACTTGAAGCCGATCGCGGGCAGGCGCACGAA
CTCATCGAGACCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References