Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1846628..1846808 Replicon chromosome
Accession NZ_CP039992
Organism Staphylococcus aureus strain Lr3

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E1E63_RS09050 Protein ID WP_001801861.1
Coordinates 1846628..1846723 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1846751..1846808 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1E63_RS09020 1842682..1843308 + 627 WP_000669025.1 hypothetical protein -
E1E63_RS09025 1843335..1844078 + 744 WP_174840254.1 exotoxin -
E1E63_RS09030 1844105..1844857 + 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
E1E63_RS09035 1844989..1845546 - 558 WP_000864141.1 ImmA/IrrE family metallo-endopeptidase -
E1E63_RS09040 1845730..1846176 - 447 WP_000747808.1 DUF1433 domain-containing protein -
E1E63_RS09045 1846258..1846483 - 226 Protein_1738 hypothetical protein -
E1E63_RS09050 1846628..1846723 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1846751..1846808 - 58 - - Antitoxin
E1E63_RS09055 1847374..1849071 - 1698 WP_000447924.1 hypothetical protein -
E1E63_RS09060 1849049..1849903 - 855 WP_001069960.1 DNA adenine methylase -
E1E63_RS09065 1849942..1851207 - 1266 WP_000072555.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 1840917..1887939 47022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T124724 WP_001801861.1 NZ_CP039992:1846628-1846723 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T124724 NZ_CP039992:1846628-1846723 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT124724 NZ_CP039992:c1846808-1846751 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References