124005

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1820381..1821614 Replicon chromosome
Accession NZ_CP039456
Organism Changchengzhania lutea strain SM1355

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag FAF07_RS08405 Protein ID WP_142784676.1
Coordinates 1820381..1821307 (-) Length 309 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag FAF07_RS08410 Protein ID WP_142784677.1
Coordinates 1821300..1821614 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAF07_RS08375 1816066..1816359 + 294 WP_142784670.1 GNAT family N-acetyltransferase -
FAF07_RS08380 1816641..1817042 + 402 WP_142784671.1 hypothetical protein -
FAF07_RS08385 1817088..1817342 + 255 WP_142784672.1 serine hydrolase -
FAF07_RS08390 1817455..1817913 + 459 WP_142784673.1 RidA family protein -
FAF07_RS08395 1817917..1818684 + 768 WP_142784674.1 MBL fold metallo-hydrolase -
FAF07_RS08400 1818725..1819453 + 729 WP_142784675.1 DJ-1/PfpI family protein -
FAF07_RS08405 1820381..1821307 - 927 WP_142784676.1 HipA domain-containing protein Toxin
FAF07_RS08410 1821300..1821614 - 315 WP_142784677.1 HipA N-terminal domain-containing protein Antitoxin
FAF07_RS08415 1821617..1821826 - 210 WP_142784678.1 helix-turn-helix transcriptional regulator -
FAF07_RS08420 1822336..1823457 + 1122 WP_142784679.1 ATP-binding protein -
FAF07_RS08425 1823479..1824696 - 1218 WP_142784680.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1788224..1824888 36664


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(52-276)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 309 a.a.        Molecular weight: 35551.29 Da        Isoelectric Point: 8.6703

>T124005 WP_142784676.1 NZ_CP039456:c1821307-1820381 [Changchengzhania lutea]
MNRCPITYELCGTNTYSEKGMRMIAPKLTHLNDLPYTAVELRQEAANRAKKLSIQGVQPKLSASVSIVDQEFKIVDQFGT
YIIKPQNDLFPQLPENEDVTMHMAKAFGLEVPFHGMLYGKDGSLSYFIKRFDRYGKGKKWATEDFAQLTGNTRDTKYRFT
MEKLIPVLDEYCSFPAIEKANFFKRILFCYLTGNEDMHLKNFSLITKNGKTTLSPIYDFLNSTIAIKNPDEEIALTMKGK
KSNLKATDFIDYFAKERLQLNEKTITIILEQIKKATPVWKELLDISFLSSDMKIKYLELLETRIVMFE

Download         Length: 927 bp

>T124005 NZ_CP039456:c1821307-1820381 [Changchengzhania lutea]
ATGAATAGATGTCCCATTACATACGAATTATGCGGTACGAATACCTATAGCGAAAAAGGAATGCGTATGATTGCACCTAA
ATTAACGCACTTAAACGATTTACCTTATACAGCAGTAGAATTACGGCAAGAGGCCGCTAATAGAGCTAAAAAGCTATCGA
TTCAAGGCGTACAACCAAAGCTTAGTGCATCTGTTTCTATTGTGGATCAAGAATTTAAAATTGTTGATCAATTTGGAACC
TATATCATAAAGCCACAAAATGATTTATTTCCACAATTACCAGAAAACGAAGATGTAACCATGCACATGGCAAAAGCATT
TGGTTTAGAAGTTCCTTTTCACGGAATGCTTTATGGTAAAGATGGTAGTTTATCCTATTTTATCAAACGTTTTGACCGTT
ATGGTAAAGGAAAAAAATGGGCTACAGAAGATTTTGCACAATTAACCGGAAATACCAGAGATACAAAATACCGTTTTACA
ATGGAGAAACTCATTCCGGTACTTGACGAATATTGTTCATTCCCTGCTATTGAAAAAGCTAATTTTTTCAAAAGAATACT
TTTTTGTTATCTAACTGGAAATGAAGATATGCACTTGAAAAACTTTTCGTTGATTACTAAAAATGGTAAAACGACCCTCT
CACCCATTTATGATTTTCTAAATTCTACTATAGCTATTAAAAATCCAGATGAAGAAATAGCGCTAACCATGAAAGGAAAA
AAAAGTAATTTAAAAGCAACAGATTTTATTGACTATTTCGCAAAAGAGAGGTTGCAACTCAATGAAAAAACAATAACTAT
AATTCTAGAACAAATAAAAAAAGCAACTCCTGTTTGGAAGGAATTGCTTGATATTTCTTTTCTATCTAGTGATATGAAAA
TAAAATATTTGGAACTATTGGAAACTAGAATAGTTATGTTTGAATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11647.34 Da        Isoelectric Point: 4.5994

>AT124005 WP_142784677.1 NZ_CP039456:c1821614-1821300 [Changchengzhania lutea]
MRQAIILAHGKRAGILTEIAADDYNFQYDQNYEGEAVSLTMPTNLKKYGYKSFPPFFEGLLPEGVMLEGLLRIAKLDKKD
YFSQLIATGNDLVGSVTVQLLENE

Download         Length: 315 bp

>AT124005 NZ_CP039456:c1821614-1821300 [Changchengzhania lutea]
ATGAGACAAGCAATAATATTGGCTCACGGAAAAAGAGCTGGAATTTTAACAGAAATAGCTGCCGACGACTATAATTTTCA
GTACGATCAAAATTATGAAGGTGAAGCGGTATCATTAACTATGCCTACAAACCTCAAAAAATATGGCTACAAATCCTTCC
CTCCTTTTTTCGAAGGGTTATTGCCTGAAGGTGTCATGTTGGAAGGATTATTGCGGATTGCCAAACTTGACAAAAAAGAT
TATTTCTCTCAACTAATTGCTACAGGAAATGATTTAGTAGGATCTGTAACAGTTCAATTATTGGAAAATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References