Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1820381..1821614 Replicon chromosome
Accession NZ_CP039456
Organism Changchengzhania lutea strain SM1355

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag FAF07_RS08405 Protein ID WP_142784676.1
Coordinates 1820381..1821307 (-) Length 309 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag FAF07_RS08410 Protein ID WP_142784677.1
Coordinates 1821300..1821614 (-) Length 105 a.a.

Genomic Context

FAF07_RS08375FAF07_RS08380FAF07_RS08385FAF07_RS08390FAF07_RS08395FAF07_RS08400FAF07_RS08420FAF07_RS08405FAF07_RS08410FAF07_RS08415FAF07_RS08425
Location: 1816066..1816359 (294 bp)
Type: Others
Protein ID: WP_142784670.1
Location: 1816641..1817042 (402 bp)
Type: Others
Protein ID: WP_142784671.1
Location: 1817088..1817342 (255 bp)
Type: Others
Protein ID: WP_142784672.1
Location: 1817455..1817913 (459 bp)
Type: Others
Protein ID: WP_142784673.1
Location: 1817917..1818684 (768 bp)
Type: Others
Protein ID: WP_142784674.1
Location: 1818725..1819453 (729 bp)
Type: Others
Protein ID: WP_142784675.1
Location: 1822336..1823457 (1122 bp)
Type: Others
Protein ID: WP_142784679.1
Location: 1820381..1821307 (927 bp)
Type: Toxin
Protein ID: WP_142784676.1
Location: 1821300..1821614 (315 bp)
Type: Antitoxin
Protein ID: WP_142784677.1
Location: 1821617..1821826 (210 bp)
Type: Others
Protein ID: WP_142784678.1
Location: 1823479..1824696 (1218 bp)
Type: Others
Protein ID: WP_142784680.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FAF07_RS083751816066..1816359+294WP_142784670.1GNAT family N-acetyltransferase-
FAF07_RS083801816641..1817042+402WP_142784671.1hypothetical protein-
FAF07_RS083851817088..1817342+255WP_142784672.1serine hydrolase-
FAF07_RS083901817455..1817913+459WP_142784673.1RidA family protein-
FAF07_RS083951817917..1818684+768WP_142784674.1MBL fold metallo-hydrolase-
FAF07_RS084001818725..1819453+729WP_142784675.1DJ-1/PfpI family protein-
FAF07_RS084051820381..1821307-927WP_142784676.1HipA domain-containing proteinToxin
FAF07_RS084101821300..1821614-315WP_142784677.1HipA N-terminal domain-containing proteinAntitoxin
FAF07_RS084151821617..1821826-210WP_142784678.1helix-turn-helix transcriptional regulator-
FAF07_RS084201822336..1823457+1122WP_142784679.1ATP-binding protein-
FAF07_RS084251823479..1824696-1218WP_142784680.1site-specific integrase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1788224..182488836664


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(52-276)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 309 a.a.        Molecular weight: 35551.29 Da        Isoelectric Point: 8.6703

>T124005 WP_142784676.1 NZ_CP039456:c1821307-1820381 [Changchengzhania lutea]
MNRCPITYELCGTNTYSEKGMRMIAPKLTHLNDLPYTAVELRQEAANRAKKLSIQGVQPKLSASVSIVDQEFKIVDQFGT
YIIKPQNDLFPQLPENEDVTMHMAKAFGLEVPFHGMLYGKDGSLSYFIKRFDRYGKGKKWATEDFAQLTGNTRDTKYRFT
MEKLIPVLDEYCSFPAIEKANFFKRILFCYLTGNEDMHLKNFSLITKNGKTTLSPIYDFLNSTIAIKNPDEEIALTMKGK
KSNLKATDFIDYFAKERLQLNEKTITIILEQIKKATPVWKELLDISFLSSDMKIKYLELLETRIVMFE

Download         Length: 927 bp

>T124005 NZ_CP039456:c1821307-1820381 [Changchengzhania lutea]
ATGAATAGATGTCCCATTACATACGAATTATGCGGTACGAATACCTATAGCGAAAAAGGAATGCGTATGATTGCACCTAA
ATTAACGCACTTAAACGATTTACCTTATACAGCAGTAGAATTACGGCAAGAGGCCGCTAATAGAGCTAAAAAGCTATCGA
TTCAAGGCGTACAACCAAAGCTTAGTGCATCTGTTTCTATTGTGGATCAAGAATTTAAAATTGTTGATCAATTTGGAACC
TATATCATAAAGCCACAAAATGATTTATTTCCACAATTACCAGAAAACGAAGATGTAACCATGCACATGGCAAAAGCATT
TGGTTTAGAAGTTCCTTTTCACGGAATGCTTTATGGTAAAGATGGTAGTTTATCCTATTTTATCAAACGTTTTGACCGTT
ATGGTAAAGGAAAAAAATGGGCTACAGAAGATTTTGCACAATTAACCGGAAATACCAGAGATACAAAATACCGTTTTACA
ATGGAGAAACTCATTCCGGTACTTGACGAATATTGTTCATTCCCTGCTATTGAAAAAGCTAATTTTTTCAAAAGAATACT
TTTTTGTTATCTAACTGGAAATGAAGATATGCACTTGAAAAACTTTTCGTTGATTACTAAAAATGGTAAAACGACCCTCT
CACCCATTTATGATTTTCTAAATTCTACTATAGCTATTAAAAATCCAGATGAAGAAATAGCGCTAACCATGAAAGGAAAA
AAAAGTAATTTAAAAGCAACAGATTTTATTGACTATTTCGCAAAAGAGAGGTTGCAACTCAATGAAAAAACAATAACTAT
AATTCTAGAACAAATAAAAAAAGCAACTCCTGTTTGGAAGGAATTGCTTGATATTTCTTTTCTATCTAGTGATATGAAAA
TAAAATATTTGGAACTATTGGAAACTAGAATAGTTATGTTTGAATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11647.34 Da        Isoelectric Point: 4.5994

>AT124005 WP_142784677.1 NZ_CP039456:c1821614-1821300 [Changchengzhania lutea]
MRQAIILAHGKRAGILTEIAADDYNFQYDQNYEGEAVSLTMPTNLKKYGYKSFPPFFEGLLPEGVMLEGLLRIAKLDKKD
YFSQLIATGNDLVGSVTVQLLENE

Download         Length: 315 bp

>AT124005 NZ_CP039456:c1821614-1821300 [Changchengzhania lutea]
ATGAGACAAGCAATAATATTGGCTCACGGAAAAAGAGCTGGAATTTTAACAGAAATAGCTGCCGACGACTATAATTTTCA
GTACGATCAAAATTATGAAGGTGAAGCGGTATCATTAACTATGCCTACAAACCTCAAAAAATATGGCTACAAATCCTTCC
CTCCTTTTTTCGAAGGGTTATTGCCTGAAGGTGTCATGTTGGAAGGATTATTGCGGATTGCCAAACTTGACAAAAAAGAT
TATTTCTCTCAACTAATTGCTACAGGAAATGATTTAGTAGGATCTGTAACAGTTCAATTATTGGAAAATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References