Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 66577..67167 Replicon chromosome
Accession NZ_CP039383
Organism Luteimonas yindakuii strain S-1072

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag E5843_RS00305 Protein ID WP_141066112.1
Coordinates 66577..66858 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag E5843_RS00310 Protein ID WP_134675356.1
Coordinates 66877..67167 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5843_RS00280 62644..64011 + 1368 WP_208542757.1 magnesium transporter -
E5843_RS00285 64195..64707 - 513 WP_136411468.1 SRPBCC family protein -
E5843_RS00290 64928..65329 - 402 WP_141065534.1 hypothetical protein -
E5843_RS00295 65370..65921 - 552 WP_136411470.1 hypothetical protein -
E5843_RS00300 66152..66370 + 219 WP_134675358.1 polyprenyl synthetase -
E5843_RS00305 66577..66858 + 282 WP_141066112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E5843_RS00310 66877..67167 + 291 WP_134675356.1 HigA family addiction module antidote protein Antitoxin
E5843_RS00315 67201..68112 + 912 WP_136411471.1 restriction endonuclease -
E5843_RS00320 68348..69565 + 1218 WP_136411472.1 RtcB family protein -
E5843_RS00325 69724..70734 + 1011 WP_136411473.1 NAD(P)-dependent alcohol dehydrogenase -
E5843_RS00330 70817..71371 + 555 WP_141066113.1 YdeI/OmpD-associated family protein -
E5843_RS00335 71476..71799 + 324 WP_141065535.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-67)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10953.54 Da        Isoelectric Point: 11.0585

>T123856 WP_141066112.1 NZ_CP039383:66577-66858 [Luteimonas yindakuii]
VIRSFADREAEKIWRGERSRRLPMDIQQTARRKLRMLNAAAVLDDLRIPPANRLEALKGERKGQHSIRINDQWRICFRWT
EGGASDVQIVDYH

Download         Length: 282 bp

>T123856 NZ_CP039383:66577-66858 [Luteimonas yindakuii]
GTGATACGGAGTTTCGCCGACAGGGAAGCGGAGAAGATCTGGCGCGGCGAACGCTCGCGCAGGTTGCCTATGGATATCCA
GCAGACTGCCCGGCGCAAGCTGCGCATGCTCAATGCCGCCGCGGTGCTCGACGACCTGCGTATCCCCCCGGCGAACCGGC
TTGAAGCGCTCAAGGGCGAGCGCAAGGGCCAGCACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCAGATGGACG
GAAGGCGGGGCCAGCGACGTCCAGATCGTCGATTACCACTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10349.03 Da        Isoelectric Point: 10.1954

>AT123856 WP_134675356.1 NZ_CP039383:66877-67167 [Luteimonas yindakuii]
MAALSNVHPGEVLQEEFLMPLGISQNALARAMAVPPRRINEIVLGKRGVTADTAVRLAAALGTSERFWLGLQADYDLEEA
RRALGSLPGRIKRLAA

Download         Length: 291 bp

>AT123856 NZ_CP039383:66877-67167 [Luteimonas yindakuii]
ATGGCTGCCTTGTCCAATGTCCACCCAGGCGAAGTGCTGCAGGAAGAGTTCCTGATGCCGCTGGGTATCAGCCAGAATGC
GCTGGCCCGCGCCATGGCCGTGCCTCCGCGTCGTATCAACGAGATCGTGCTGGGCAAGCGCGGCGTTACCGCCGACACCG
CCGTGCGCCTGGCTGCGGCCCTGGGCACCAGCGAGCGCTTCTGGCTCGGTCTGCAGGCTGACTACGATCTGGAAGAAGCG
CGCCGCGCGCTGGGCAGCCTGCCCGGCAGGATCAAGCGACTGGCAGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References