Detailed information of TA system TA123763

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 3139336..3139768
• Replicon: chromosome
• Accession: NZ_CP039296
• Organism: Enterococcus faecalis strain VE14089

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: A0A4U3MBY2
• Locus tag: E7T02_RS16650
• Protein ID: WP_002372618.1
• Coordinates: 3139571..3139768 (+)
• Length: 66 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	3139336..3139512 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
-	3144312..3144455	+	144	-	-	-
-	3144059..3144201	-	143	-	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (32-65)

Sequences

Toxin

Protein

• Length: 66 a.a.
• Molecular weight: 7516.13 Da
• Isoelectric Point: 10.5649

>T123763 WP_002372618.1 NZ_CP039296:3139571-3139768 [Enterococcus faecalis]
MCREVMAVAIQSEREVMRMHVFPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 198 bp

>T123763 NZ_CP039296:3139571-3139768 [Enterococcus faecalis]
ATGTGTAGAGAAGTTATGGCGGTGGCTATCCAATCTGAAAGAGAGGTGATGCGTATGCACGTATTTCCGAAATTCACAGA
AAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGGTATGTTTACCATTGCTTTGATTGCGC
TGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin

Nucleotide

• Length: 177 bp

>AT123763 NZ_CP039296:c3139512-3139336 [Enterococcus faecalis]
TGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGACGGTGACCTTTT
GGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAACAGCTTTTAGGATTCCG
AAGATTAACGTTGCGAT

Structures

Toxin

• AlphaFold DB: A0A4U3MBY2

Antitoxin