Detailed information of TA system TA123760

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 3091722..3091936
• Replicon: chromosome
• Accession: NZ_CP039296
• Organism: Enterococcus faecalis strain VE14089

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: E7T02_RS16405
• Protein ID: WP_107164701.1
• Coordinates: 3091722..3091832 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	3091872..3091936 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E7T02_RS16355	3086847..3087209	-	363	WP_000241511.1	type II toxin-antitoxin system PemK/MazF family toxin	-
E7T02_RS16360	3087203..3087466	-	264	WP_000245205.1	PbsX family transcriptional regulator	-
E7T02_RS16365	3087643..3088263	+	621	WP_021732893.1	recombinase family protein	-
E7T02_RS16370	3088280..3088567	+	288	WP_010708491.1	hypothetical protein	-
E7T02_RS16375	3088561..3088785	+	225	WP_010708492.1	hypothetical protein	-
E7T02_RS16380	3088846..3089055	+	210	WP_002387638.1	hypothetical protein	-
E7T02_RS16385	3089067..3089369	+	303	WP_002365939.1	hypothetical protein	-
E7T02_RS16390	3089796..3091124	+	1329	WP_002387639.1	Y-family DNA polymerase	-
E7T02_RS16395	3091121..3091471	+	351	WP_002365943.1	hypothetical protein	-
E7T02_RS16405	3091722..3091832	+	111	WP_107164701.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	3091872..3091936	-	65	-	-	Antitoxin
-	3091872..3091974	-	103	NuclAT_2	-	-
-	3091872..3091974	-	103	NuclAT_2	-	-
-	3091872..3091974	-	103	NuclAT_2	-	-
-	3091872..3091974	-	103	NuclAT_2	-	-
E7T02_RS16410	3092171..3092632	+	462	WP_002365946.1	hypothetical protein	-
E7T02_RS16415	3092803..3093093	+	291	WP_002365947.1	hypothetical protein	-
E7T02_RS16420	3093197..3093568	-	372	WP_000049959.1	replication-associated protein RepC	-
E7T02_RS16425	3093561..3094406	-	846	WP_000239313.1	AAA family ATPase	-
E7T02_RS16435	3094878..3095888	+	1011	WP_002365949.1	replication initiator protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4090.89 Da
• Isoelectric Point: 4.1672

>T123760 WP_107164701.1 NZ_CP039296:3091722-3091832 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 111 bp

>T123760 NZ_CP039296:3091722-3091832 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCAATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAGCCGAAAGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT123760 NZ_CP039296:c3091936-3091872 [Enterococcus faecalis]
AACGACATTAAATCGTACAGATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin