Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1605682..1606217 Replicon chromosome
Accession NZ_CP039292
Organism Actinomyces procaprae strain dk561

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag E4J16_RS06440 Protein ID WP_136193031.1
Coordinates 1605682..1605942 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag E4J16_RS06445 Protein ID WP_136193030.1
Coordinates 1605954..1606217 (-) Length 88 a.a.

Genomic Context

E4J16_RS06415E4J16_RS06420E4J16_RS06425E4J16_RS06430E4J16_RS06435E4J16_RS06440E4J16_RS06445E4J16_RS06450
Location: 1601465..1602946 (1482 bp)
Type: Others
Protein ID: WP_136193036.1
Location: 1602954..1603373 (420 bp)
Type: Others
Protein ID: WP_136313554.1
Location: 1603370..1604044 (675 bp)
Type: Others
Protein ID: WP_136193034.1
Location: 1604049..1605053 (1005 bp)
Type: Others
Protein ID: WP_136193033.1
Location: 1605192..1605692 (501 bp)
Type: Others
Protein ID: WP_136193032.1
Location: 1605682..1605942 (261 bp)
Type: Toxin
Protein ID: WP_136193031.1
Location: 1605954..1606217 (264 bp)
Type: Antitoxin
Protein ID: WP_136193030.1
Location: 1606214..1606867 (654 bp)
Type: Others
Protein ID: WP_136313555.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E4J16_RS064151601465..1602946-1482WP_136193036.1sodium/proline symporter PutP-
E4J16_RS064201602954..1603373-420WP_136313554.1dihydroxyacetone kinase-
E4J16_RS064251603370..1604044-675WP_136193034.1dihydroxyacetone kinase subunit L-
E4J16_RS064301604049..1605053-1005WP_136193033.1dihydroxyacetone kinase subunit DhaK-
E4J16_RS064351605192..1605692-501WP_136193032.1holo-ACP synthase-
E4J16_RS064401605682..1605942-261WP_136193031.1Txe/YoeB family addiction module toxinToxin
E4J16_RS064451605954..1606217-264WP_136193030.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
E4J16_RS064501606214..1606867-654WP_136313555.1GNAT family N-acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10168.61 Da        Isoelectric Point: 9.6240

>T123735 WP_136193031.1 NZ_CP039292:c1605942-1605682 [Actinomyces procaprae]
MRLIWSTHAWEDYLWWQAEDRRVLERVNLLLQDIQRHGSEGPGKPVALRGNLSGYWSRRITAEHRLVYRVGGDDILVVAC
RLHYGR

Download         Length: 261 bp

>T123735 NZ_CP039292:c1605942-1605682 [Actinomyces procaprae]
ATGCGACTCATCTGGTCTACCCACGCCTGGGAGGACTACCTGTGGTGGCAGGCTGAGGATCGTCGAGTGCTCGAACGCGT
CAATCTCCTCCTCCAGGACATCCAACGGCACGGCAGCGAGGGACCCGGCAAGCCTGTGGCCCTCCGCGGCAATCTCAGCG
GCTACTGGTCGCGTCGCATCACCGCCGAGCACAGGCTCGTTTACCGGGTCGGTGGGGATGACATTCTCGTCGTTGCGTGC
AGGCTCCACTATGGGCGTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9831.97 Da        Isoelectric Point: 4.5686

>AT123735 WP_136193030.1 NZ_CP039292:c1606217-1605954 [Actinomyces procaprae]
MRTMTYTESRARYAQVLNDVVDDREEVVITRAGHDPAVIVSLAEYEALKETAYLLRNPANARRLLESITELEEGRGKAHE
LVNTGED

Download         Length: 264 bp

>AT123735 NZ_CP039292:c1606217-1605954 [Actinomyces procaprae]
ATGAGGACCATGACCTACACGGAGTCCCGCGCACGCTACGCCCAAGTGCTCAATGACGTGGTGGACGACCGCGAGGAGGT
CGTCATCACTCGAGCCGGGCACGATCCCGCCGTCATCGTCTCCCTAGCTGAGTATGAGGCGCTCAAGGAGACCGCTTATC
TCCTGCGCAACCCCGCCAACGCCAGACGGCTCCTGGAGTCGATCACCGAGCTCGAGGAAGGGCGCGGCAAGGCCCACGAG
CTGGTGAACACCGGTGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References