Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1878808..1878988 Replicon chromosome
Accession NZ_CP039167
Organism Staphylococcus aureus strain R50

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E1952_RS09480 Protein ID WP_001801861.1
Coordinates 1878808..1878903 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1878931..1878988 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1952_RS09450 1874862..1875488 + 627 WP_000669025.1 hypothetical protein -
E1952_RS09455 1875515..1876258 + 744 WP_174840254.1 exotoxin -
E1952_RS09460 1876285..1877037 + 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
E1952_RS09465 1877169..1877726 - 558 WP_000864141.1 ImmA/IrrE family metallo-endopeptidase -
E1952_RS09470 1877910..1878356 - 447 WP_000747808.1 DUF1433 domain-containing protein -
E1952_RS09480 1878808..1878903 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1878931..1878988 - 58 - - Antitoxin
E1952_RS09485 1879554..1881251 - 1698 WP_000447924.1 hypothetical protein -
E1952_RS09490 1881229..1882083 - 855 WP_001069960.1 DNA adenine methylase -
E1952_RS09495 1882122..1883387 - 1266 WP_000072555.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 1872303..1900612 28309


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T123625 WP_001801861.1 NZ_CP039167:1878808-1878903 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T123625 NZ_CP039167:1878808-1878903 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT123625 NZ_CP039167:c1878988-1878931 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References