123609

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2092610..2092826 Replicon chromosome
Accession NZ_CP039162
Organism Staphylococcus aureus strain Lr12

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E1950_RS10655 Protein ID WP_001802298.1
Coordinates 2092722..2092826 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2092610..2092665 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1950_RS10635 2088816..2089481 - 666 WP_001024095.1 SDR family oxidoreductase -
E1950_RS10640 2089633..2089953 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E1950_RS10645 2089955..2090932 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
E1950_RS10650 2091198..2092289 + 1092 WP_000495669.1 hypothetical protein -
- 2092610..2092665 + 56 - - Antitoxin
E1950_RS10655 2092722..2092826 - 105 WP_001802298.1 hypothetical protein Toxin
E1950_RS10665 2093506..2093664 + 159 WP_001792784.1 hypothetical protein -
E1950_RS10675 2094322..2095179 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
E1950_RS10680 2095247..2096029 - 783 WP_103152256.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T123609 WP_001802298.1 NZ_CP039162:c2092826-2092722 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T123609 NZ_CP039162:c2092826-2092722 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT123609 NZ_CP039162:2092610-2092665 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References