Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1836320..1836500 Replicon chromosome
Accession NZ_CP039160
Organism Staphylococcus aureus strain Lr6

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E1949_RS09165 Protein ID WP_001801861.1
Coordinates 1836320..1836415 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1836443..1836500 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1949_RS09130 1832112..1832738 + 627 WP_000669025.1 hypothetical protein -
E1949_RS09135 1832765..1833508 + 744 WP_174840254.1 exotoxin -
E1949_RS09140 1833535..1834287 + 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
E1949_RS09145 1834419..1834976 - 558 WP_000864141.1 ImmA/IrrE family metallo-endopeptidase -
E1949_RS09150 1835160..1835423 - 264 Protein_1764 hypothetical protein -
E1949_RS09160 1835950..1836175 - 226 Protein_1765 hypothetical protein -
E1949_RS09165 1836320..1836415 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1836443..1836500 - 58 - - Antitoxin
E1949_RS09170 1837066..1838763 - 1698 WP_000447924.1 hypothetical protein -
E1949_RS09175 1838741..1839595 - 855 WP_001069960.1 DNA adenine methylase -
E1949_RS09180 1839634..1840899 - 1266 WP_000072555.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 1830347..1860757 30410


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T123589 WP_001801861.1 NZ_CP039160:1836320-1836415 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T123589 NZ_CP039160:1836320-1836415 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT123589 NZ_CP039160:c1836500-1836443 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References