Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2533842..2534026 Replicon chromosome
Accession NZ_CP038612
Organism Staphylococcus aureus strain O268

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SaO268_RS13285 Protein ID WP_000482647.1
Coordinates 2533919..2534026 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2533842..2533902 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO268_RS13260 2529296..2529463 - 168 WP_041204334.1 hypothetical protein -
SaO268_RS13270 2529694..2531427 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
SaO268_RS13275 2531452..2533215 - 1764 WP_001064817.1 ABC transporter ATP-binding protein/permease -
- 2533842..2533902 + 61 - - Antitoxin
SaO268_RS13285 2533919..2534026 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SaO268_RS13290 2534159..2534545 - 387 WP_000779350.1 flippase GtxA -
SaO268_RS13295 2534813..2535955 + 1143 WP_001176868.1 glycerate kinase -
SaO268_RS13300 2536015..2536674 + 660 WP_000831299.1 hypothetical protein -
SaO268_RS13305 2536860..2538071 + 1212 WP_001191928.1 multidrug effflux MFS transporter -
SaO268_RS13310 2538194..2538667 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T123073 WP_000482647.1 NZ_CP038612:c2534026-2533919 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T123073 NZ_CP038612:c2534026-2533919 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT123073 NZ_CP038612:2533842-2533902 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References