Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2245131..2245329 Replicon chromosome
Accession NZ_CP038612
Organism Staphylococcus aureus strain O268

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SaO268_RS11750 Protein ID WP_001802298.1
Coordinates 2245225..2245329 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2245131..2245169 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO268_RS11730 2241182..2241847 - 666 WP_001024100.1 SDR family oxidoreductase -
SaO268_RS11735 2241999..2242319 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SaO268_RS11740 2242321..2243301 + 981 WP_000019740.1 CDF family zinc efflux transporter CzrB -
SaO268_RS11745 2243567..2244658 + 1092 WP_000495692.1 hypothetical protein -
- 2245131..2245169 + 39 - - Antitoxin
SaO268_RS11750 2245225..2245329 - 105 WP_001802298.1 hypothetical protein Toxin
SaO268_RS14855 2245490..2245973 - 484 Protein_2189 recombinase family protein -
SaO268_RS11760 2246016..2247136 - 1121 Protein_2190 SAP domain-containing protein -
SaO268_RS11765 2248185..2249042 - 858 WP_000370943.1 Cof-type HAD-IIB family hydrolase -
SaO268_RS11770 2249110..2249892 - 783 WP_000909235.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T123071 WP_001802298.1 NZ_CP038612:c2245329-2245225 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T123071 NZ_CP038612:c2245329-2245225 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT123071 NZ_CP038612:2245131-2245169 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References