Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1885656..1885836 Replicon chromosome
Accession NZ_CP038612
Organism Staphylococcus aureus strain O268

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SaO268_RS09540 Protein ID WP_001801861.1
Coordinates 1885656..1885751 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1885779..1885836 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO268_RS09505 1881060..1881686 + 627 WP_000669034.1 hypothetical protein -
SaO268_RS09510 1881727..1882068 + 342 WP_000627544.1 DUF3969 family protein -
SaO268_RS09515 1882169..1882741 + 573 WP_000414210.1 hypothetical protein -
SaO268_RS09520 1883117..1883953 + 837 WP_000190484.1 ABC transporter ATP-binding protein -
SaO268_RS09530 1884759..1885205 - 447 WP_000747806.1 DUF1433 domain-containing protein -
SaO268_RS09540 1885656..1885751 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1885779..1885836 - 58 - - Antitoxin
SaO268_RS09545 1885874..1885975 + 102 WP_001791232.1 hypothetical protein -
SaO268_RS09550 1885961..1886140 - 180 Protein_1805 transposase -
SaO268_RS09555 1886328..1886702 - 375 WP_000695817.1 DUF1433 domain-containing protein -
SaO268_RS09560 1886692..1887072 - 381 WP_001035978.1 DUF1433 domain-containing protein -
SaO268_RS09565 1887280..1887720 - 441 WP_000759945.1 DUF1433 domain-containing protein -
SaO268_RS09570 1887765..1889378 + 1614 WP_000926709.1 hypothetical protein -
SaO268_RS09575 1889393..1889692 + 300 WP_000095391.1 WXG100 family type VII secretion target -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T123065 WP_001801861.1 NZ_CP038612:1885656-1885751 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T123065 NZ_CP038612:1885656-1885751 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT123065 NZ_CP038612:c1885836-1885779 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References