Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4649936..4651287 Replicon chromosome
Accession NZ_CP038498
Organism Pectobacterium punjabense strain SS95

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag E2566_RS21045 Protein ID WP_107169321.1
Coordinates 4650247..4651287 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag E2566_RS21040 Protein ID WP_107169320.1
Coordinates 4649936..4650250 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2566_RS21015 4645771..4646805 + 1035 WP_107169315.1 putative FMN-dependent luciferase-like monooxygenase -
E2566_RS21020 4646802..4647935 + 1134 WP_107169316.1 alkylhydroperoxidase domain protein -
E2566_RS21025 4647992..4648504 - 513 WP_165800648.1 phenolic acid decarboxylase -
E2566_RS21030 4648604..4649476 + 873 WP_107169318.1 LysR family transcriptional regulator -
E2566_RS21035 4649625..4649951 + 327 WP_107169319.1 helix-turn-helix domain-containing protein -
E2566_RS21040 4649936..4650250 + 315 WP_107169320.1 HipA N-terminal domain-containing protein Antitoxin
E2566_RS21045 4650247..4651287 + 1041 WP_107169321.1 HipA domain-containing protein Toxin
E2566_RS21050 4651348..4651971 - 624 WP_107169322.1 LysE family translocator -
E2566_RS21055 4652015..4652554 - 540 WP_107169323.1 CbrC family protein -
E2566_RS21060 4652755..4653510 + 756 WP_107169324.1 thiol:disulfide interchange protein DsbG -
E2566_RS21065 4653545..4654450 - 906 WP_107169325.1 siderophore-interacting protein -
E2566_RS21070 4654933..4655535 + 603 WP_107169326.1 RhiA -
E2566_RS21075 4655604..4655963 + 360 WP_107169327.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-306)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39466.49 Da        Isoelectric Point: 6.7365

>T122995 WP_107169321.1 NZ_CP038498:4650247-4651287 [Pectobacterium punjabense]
MTRCRILLTPLAHEEEIATGYSRKGLKHLAGSIHASPTLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLEDRAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMERLGFSVPPHGLLRFKPKQVDDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYVSYERLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGQLILAPIYDFVSV
APYPAYFSSCFMALPLLIQEEGDEVLAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFIKEAGCVESTYRDSFMP
ADAIDATLQCYRHRLNLMSILDAKRI

Download         Length: 1041 bp

>T122995 NZ_CP038498:4650247-4651287 [Pectobacterium punjabense]
ATGACAAGATGTCGAATTTTACTGACGCCTCTGGCACATGAAGAAGAAATTGCCACAGGCTATAGCCGTAAAGGATTGAA
GCATCTTGCGGGGTCAATACATGCTTCCCCAACCTTACGTTTCACACGCCAGCAATTCATGCACGACTTGCCACAAACGC
AGAAAGGCATGAGTATTTCTGGTTATCAGCCCAAGATTCAGATGGTATTAGAAGATCGGGCGTTTACCGTCGTTGACCAC
CAAGGTCTGTATATTCTTAAACCCTCTCCAATTGAATTTCCCCATTTGGCAGAAAACGAACACGCCACCATGACGCTCAT
GGAACGTCTGGGGTTTTCCGTGCCACCGCACGGGTTGCTCCGTTTTAAACCGAAACAAGTTGATGACGAACCTGAGTTTG
CTTTCGTTATTAAGCGCTTCGACCGAGACGAAAAAACAGGTCACCCTATCCATCAGGAACAGTTGGATGGTGCAATGGGG
ATCGGTGAAAAATTCGGTAAAATACGCGCAGATGGCAGACAATATGTCAGTTATGAGAGGTTGGCGTTATTCCTTAGCGA
GCACGTTAATGACAATATCGTCTTCAAAATTGATCTATTCCGCCGCATTGCTTATGCCTATATGCTGGGTAACAATGACA
TGCACCTGCGTAATTTTGGCCTGATACATTCGCGTTCAGGCCAGTTAATACTAGCTCCCATTTATGATTTTGTTTCCGTC
GCCCCTTATCCCGCCTATTTTTCTTCCTGCTTCATGGCATTACCGCTGTTGATCCAAGAAGAAGGTGACGAGGTACTCGC
ACCAGGGTTTGAAACCGCGTATGGGGAATACCTTGGTATGGATTTCATACTGTTTGGCCAGCGTATCGGGCTGAGTGAAA
ATCTCACCAAGAAGCTACTAGCTGACTTCATAAAAGAAGCTGGATGCGTTGAATCAACCTATCGGGATTCTTTTATGCCT
GCGGACGCGATTGATGCAACGCTACAGTGCTATCGACACCGTCTGAATCTTATGAGTATTCTCGATGCAAAGCGGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11905.68 Da        Isoelectric Point: 9.2317

>AT122995 WP_107169320.1 NZ_CP038498:4649936-4650250 [Pectobacterium punjabense]
MRRQIKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKSLPPYFASLAPEGWLRRQYSQFQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKA

Download         Length: 315 bp

>AT122995 NZ_CP038498:4649936-4650250 [Pectobacterium punjabense]
ATGCGCCGTCAGATAAAGGTCTATCTTTACGGTGTCCATATCGGCCAGTTAAGTCAGGATGATGAAGGCTATCTGTTTGA
ATATAAAAAGTCCTACATCGGCCCGCCATTATCACTAAGCCTACCGATACAGACCGGAACATTTCGTAGCAAATCATTGC
CACCCTATTTTGCCTCGTTGGCGCCGGAAGGCTGGTTGCGGCGACAGTACAGCCAGTTTCAACATCTGGATGAGAAGGAT
TTATTTGGCATCCTCATTCAAAACGGTAAGAACCTAATCGGCGCAGTACAACTGATCGCAGAGGATAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References