122868

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 2168474..2168671 Replicon chromosome
Accession NZ_CP038461
Organism Staphylococcus aureus strain O217

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag SaO217_RS10550 Protein ID WP_073392962.1
Coordinates 2168567..2168671 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2168474..2168512 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO217_RS10530 2164649..2165314 - 666 WP_001024099.1 SDR family oxidoreductase -
SaO217_RS10535 2165466..2165786 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SaO217_RS10540 2165788..2166768 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
SaO217_RS10545 2167034..2168125 + 1092 WP_000495684.1 hypothetical protein -
- 2168474..2168512 + 39 - - Antitoxin
SaO217_RS10550 2168567..2168671 - 105 WP_073392962.1 hypothetical protein Toxin
SaO217_RS10555 2169351..2169509 + 159 WP_001792784.1 hypothetical protein -
SaO217_RS10560 2170168..2171025 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
SaO217_RS10565 2171093..2171875 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T122868 WP_073392962.1 NZ_CP038461:c2168671-2168567 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T122868 NZ_CP038461:c2168671-2168567 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT122868 NZ_CP038461:2168474-2168512 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References