Detailed information of TA system TA122861

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1003687..1003936
• Replicon: chromosome
• Accession: NZ_CP038461
• Organism: Staphylococcus aureus strain O217

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SaO217_RS04825
• Protein ID: WP_000623369.1
• Coordinates: 1003687..1003794 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1003789..1003936 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SaO217_RS04800	1000360..1000929	-	570	WP_000287265.1	competence protein ComK	-
SaO217_RS04805	1001139..1001357	+	219	WP_000876825.1	IDEAL domain-containing protein	-
SaO217_RS04810	1001438..1002424	-	987	WP_000668820.1	lipoate--protein ligase	-
SaO217_RS04815	1002623..1002799	+	177	WP_000214898.1	YkvS family protein	-
SaO217_RS04820	1002814..1003416	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
SaO217_RS04825	1003687..1003794	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1003789..1003936	-	148	-	-	Antitoxin
SaO217_RS04830	1004333..1004434	+	102	WP_001790623.1	hypothetical protein	-
SaO217_RS04835	1004444..1004716	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
SaO217_RS04840	1004760..1006724	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
SaO217_RS04845	1006727..1007047	+	321	WP_000873929.1	YxeA family protein	-
SaO217_RS04850	1007044..1007685	+	642	WP_000571183.1	ABC transporter ATP-binding protein	-
SaO217_RS04855	1007773..1008063	-	291	WP_001791476.1	hypothetical protein	-
SaO217_RS04860	1008404..1008691	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T122861 WP_000623369.1 NZ_CP038461:1003687-1003794 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T122861 NZ_CP038461:1003687-1003794 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT122861 NZ_CP038461:c1003936-1003789 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin