122851

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2170848..2171111 Replicon chromosome
Accession NZ_CP038460
Organism Staphylococcus aureus strain B119

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SaO322_RS11225 Protein ID WP_001802298.1
Coordinates 2171007..2171111 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2170848..2171012 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO322_RS11205 2167080..2167745 - 666 WP_001024100.1 SDR family oxidoreductase -
SaO322_RS11210 2167897..2168217 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SaO322_RS11215 2168219..2169199 + 981 WP_000019740.1 CDF family zinc efflux transporter CzrB -
SaO322_RS11220 2169465..2170556 + 1092 WP_000495692.1 hypothetical protein -
- 2170848..2171012 + 165 - - Antitoxin
SaO322_RS11225 2171007..2171111 - 105 WP_001802298.1 hypothetical protein Toxin
SaO322_RS14280 2171272..2171755 - 484 Protein_2078 recombinase family protein -
SaO322_RS11235 2171798..2172918 - 1121 Protein_2079 SAP domain-containing protein -
SaO322_RS11240 2173967..2174824 - 858 WP_000370943.1 Cof-type HAD-IIB family hydrolase -
SaO322_RS11245 2174892..2175674 - 783 WP_118848146.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T122851 WP_001802298.1 NZ_CP038460:c2171111-2171007 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T122851 NZ_CP038460:c2171111-2171007 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT122851 NZ_CP038460:2170848-2171012 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References