Detailed information of TA system TA122846

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1820758..1820938
• Replicon: chromosome
• Accession: NZ_CP038460
• Organism: Staphylococcus aureus strain B119

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SaO322_RS09080
• Protein ID: WP_001801861.1
• Coordinates: 1820758..1820853 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1820881..1820938 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SaO322_RS09045	1816162..1816788	+	627	WP_000669034.1	hypothetical protein	-
SaO322_RS09050	1816829..1817170	+	342	WP_000627544.1	DUF3969 family protein	-
SaO322_RS09055	1817271..1817843	+	573	WP_000414210.1	hypothetical protein	-
SaO322_RS09060	1818219..1819055	+	837	WP_000190484.1	ABC transporter ATP-binding protein	-
SaO322_RS09070	1819861..1820307	-	447	WP_000747806.1	DUF1433 domain-containing protein	-
SaO322_RS09080	1820758..1820853	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1820881..1820938	-	58	-	-	Antitoxin
SaO322_RS09085	1820976..1821077	+	102	WP_001791232.1	hypothetical protein	-
SaO322_RS09090	1821063..1821242	-	180	Protein_1711	transposase	-
SaO322_RS09095	1821430..1821804	-	375	WP_000695817.1	DUF1433 domain-containing protein	-
SaO322_RS09100	1821794..1822174	-	381	WP_001035978.1	DUF1433 domain-containing protein	-
SaO322_RS09105	1822382..1822822	-	441	WP_000759945.1	DUF1433 domain-containing protein	-
SaO322_RS09110	1822867..1824480	+	1614	WP_000926709.1	hypothetical protein	-
SaO322_RS09115	1824495..1824794	+	300	WP_000095391.1	WXG100 family type VII secretion target	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T122846 WP_001801861.1 NZ_CP038460:1820758-1820853 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T122846 NZ_CP038460:1820758-1820853 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT122846 NZ_CP038460:c1820938-1820881 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin