Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1856925..1857105 Replicon chromosome
Accession NZ_CP038270
Organism Staphylococcus aureus strain O408 isolate B115

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SaO408_RS09245 Protein ID WP_001801861.1
Coordinates 1856925..1857020 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1857048..1857105 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO408_RS09205 1851992..1852564 + 573 WP_000414229.1 hypothetical protein -
SaO408_RS09210 1852940..1853776 + 837 WP_000190484.1 ABC transporter ATP-binding protein -
SaO408_RS09220 1854583..1854768 - 186 WP_000809858.1 hypothetical protein -
SaO408_RS09225 1854770..1854946 - 177 WP_000375476.1 hypothetical protein -
SaO408_RS09230 1854957..1855340 - 384 WP_000070811.1 hypothetical protein -
SaO408_RS09235 1856027..1856473 - 447 WP_000747809.1 DUF1433 domain-containing protein -
SaO408_RS09245 1856925..1857020 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1857048..1857105 - 58 - - Antitoxin
SaO408_RS09250 1857143..1857244 + 102 WP_001791232.1 hypothetical protein -
SaO408_RS09255 1857282..1857398 - 117 Protein_1738 transposase -
SaO408_RS09260 1857907..1862019 - 4113 WP_000831220.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T120917 WP_001801861.1 NZ_CP038270:1856925-1857020 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T120917 NZ_CP038270:1856925-1857020 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT120917 NZ_CP038270:c1857105-1857048 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References