Detailed information of TA system TA120910

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2365736..2365920
• Replicon: chromosome
• Accession: NZ_CP038269
• Organism: Staphylococcus aureus strain O331 isolate B114

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: SaO331_RS12085
• Protein ID: WP_000482647.1
• Coordinates: 2365813..2365920 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2365736..2365796 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SaO331_RS12065	2361246..2361413	-	168	WP_031845053.1	hypothetical protein	-
SaO331_RS12075	2361644..2363377	-	1734	WP_000488493.1	ABC transporter ATP-binding protein/permease	-
SaO331_RS12080	2363402..2365165	-	1764	WP_001064822.1	ABC transporter ATP-binding protein/permease	-
SaO331_RS13725	2365619..2365786	-	168	WP_000301893.1	hypothetical protein	-
-	2365736..2365796	+	61	-	-	Antitoxin
SaO331_RS12085	2365813..2365920	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
SaO331_RS12090	2366053..2366439	-	387	WP_000779353.1	flippase GtxA	-
SaO331_RS12095	2366707..2367849	+	1143	WP_001176863.1	glycerate kinase	-
SaO331_RS12100	2367909..2368568	+	660	WP_000831298.1	membrane protein	-
SaO331_RS12105	2368751..2369962	+	1212	WP_001191921.1	multidrug effflux MFS transporter	-
SaO331_RS12110	2370085..2370558	-	474	WP_000456483.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T120910 WP_000482647.1 NZ_CP038269:c2365920-2365813 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T120910 NZ_CP038269:c2365920-2365813 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT120910 NZ_CP038269:2365736-2365796 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin