120908

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2078937..2079200 Replicon chromosome
Accession NZ_CP038269
Organism Staphylococcus aureus strain O331 isolate B114

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SaO331_RS10570 Protein ID WP_001802298.1
Coordinates 2079096..2079200 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2078937..2079101 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO331_RS10550 2075174..2075839 - 666 WP_001024088.1 SDR family oxidoreductase -
SaO331_RS10555 2075991..2076311 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SaO331_RS10560 2076313..2077290 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
SaO331_RS10565 2077556..2078647 + 1092 WP_000495695.1 hypothetical protein -
- 2078937..2079101 + 165 - - Antitoxin
SaO331_RS10570 2079096..2079200 - 105 WP_001802298.1 hypothetical protein Toxin
SaO331_RS13705 2079361..2079844 - 484 Protein_1941 recombinase family protein -
SaO331_RS10580 2079887..2081023 - 1137 Protein_1942 SAP domain-containing protein -
SaO331_RS10585 2081312..2081404 + 93 WP_031844941.1 hypothetical protein -
SaO331_RS10590 2082099..2082956 - 858 WP_031844942.1 Cof-type HAD-IIB family hydrolase -
SaO331_RS10595 2083024..2083806 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T120908 WP_001802298.1 NZ_CP038269:c2079200-2079096 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T120908 NZ_CP038269:c2079200-2079096 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT120908 NZ_CP038269:2078937-2079101 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References