Detailed information of TA system TA120900

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2483647..2483831
• Replicon: chromosome
• Accession: NZ_CP038268
• Organism: Staphylococcus aureus strain O55 isolate B118

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: SaO55_RS12925
• Protein ID: WP_000482647.1
• Coordinates: 2483724..2483831 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2483647..2483707 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SaO55_RS12900	2479101..2479268	-	168	WP_031927726.1	hypothetical protein	-
SaO55_RS12910	2479499..2481232	-	1734	WP_000486497.1	ABC transporter ATP-binding protein/permease	-
SaO55_RS12915	2481257..2483020	-	1764	WP_001064840.1	ABC transporter ATP-binding protein/permease	-
-	2483647..2483707	+	61	-	-	Antitoxin
SaO55_RS12925	2483724..2483831	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
SaO55_RS12930	2483965..2484351	-	387	WP_000779353.1	flippase GtxA	-
SaO55_RS12935	2484619..2485761	+	1143	WP_001176867.1	glycerate kinase	-
SaO55_RS12940	2485821..2486480	+	660	WP_000831298.1	membrane protein	-
SaO55_RS12945	2486663..2487874	+	1212	WP_001191927.1	multidrug effflux MFS transporter	-
SaO55_RS12950	2487997..2488470	-	474	WP_000456493.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sbi / hlgA / hlgC / hlgC / hlgB	2468422..2484351	15929

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T120900 WP_000482647.1 NZ_CP038268:c2483831-2483724 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T120900 NZ_CP038268:c2483831-2483724 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT120900 NZ_CP038268:2483647-2483707 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin