Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 70278..70797 | Replicon | chromosome |
Accession | NZ_CP038242 | ||
Organism | Staphylococcus warneri strain GD01 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A364USX6 |
Locus tag | EOJ31_RS00305 | Protein ID | WP_002466416.1 |
Coordinates | 70525..70797 (+) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A2T4PYE3 |
Locus tag | EOJ31_RS00300 | Protein ID | WP_002466398.1 |
Coordinates | 70278..70532 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EOJ31_RS00285 | 65795..67117 | + | 1323 | WP_002466404.1 | PrsW family intramembrane metalloprotease | - |
EOJ31_RS00290 | 67268..67705 | + | 438 | WP_002466379.1 | hypothetical protein | - |
EOJ31_RS00295 | 67832..70033 | - | 2202 | WP_189723475.1 | YSIRK-type signal peptide-containing protein | - |
EOJ31_RS00300 | 70278..70532 | + | 255 | WP_002466398.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EOJ31_RS00305 | 70525..70797 | + | 273 | WP_002466416.1 | Txe/YoeB family addiction module toxin | Toxin |
EOJ31_RS00310 | 71190..72560 | + | 1371 | WP_189723477.1 | citrate:proton symporter | - |
EOJ31_RS00315 | 72653..73291 | - | 639 | WP_002466369.1 | NAD(P)H-dependent oxidoreductase | - |
EOJ31_RS00320 | 73578..75008 | + | 1431 | WP_002466385.1 | multidrug efflux MFS transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10852.63 Da Isoelectric Point: 9.9029
>T120847 WP_002466416.1 NZ_CP038242:70525-70797 [Staphylococcus warneri]
MSRLNILFTPDAFEDYKYWQIHDKKLLKKINQLIKCINRNGPLEGEGKPEALKGNFKGYYSRRINFEHRLVYKVHDSEII
IVSCKYHYFK
MSRLNILFTPDAFEDYKYWQIHDKKLLKKINQLIKCINRNGPLEGEGKPEALKGNFKGYYSRRINFEHRLVYKVHDSEII
IVSCKYHYFK
Download Length: 273 bp
>T120847 NZ_CP038242:70525-70797 [Staphylococcus warneri]
ATGAGTAGATTAAATATTTTATTTACACCTGATGCATTTGAAGATTATAAATATTGGCAAATTCATGATAAAAAATTATT
AAAAAAGATTAACCAATTGATAAAATGTATAAATCGTAATGGCCCACTCGAAGGTGAAGGAAAACCTGAAGCTTTGAAAG
GTAATTTTAAAGGATATTATAGTAGAAGAATCAATTTTGAACATAGGTTAGTTTATAAAGTACATGATTCAGAAATAATT
ATTGTTTCTTGTAAATATCATTATTTTAAATAA
ATGAGTAGATTAAATATTTTATTTACACCTGATGCATTTGAAGATTATAAATATTGGCAAATTCATGATAAAAAATTATT
AAAAAAGATTAACCAATTGATAAAATGTATAAATCGTAATGGCCCACTCGAAGGTGAAGGAAAACCTGAAGCTTTGAAAG
GTAATTTTAAAGGATATTATAGTAGAAGAATCAATTTTGAACATAGGTTAGTTTATAAAGTACATGATTCAGAAATAATT
ATTGTTTCTTGTAAATATCATTATTTTAAATAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9345.27 Da Isoelectric Point: 4.0334
>AT120847 WP_002466398.1 NZ_CP038242:70278-70532 [Staphylococcus warneri]
MAIVSYSIARKNFRSLIDKVNNDSDAVTITTNDSNAVLISESDYNAMMETLYLQQSPANAQHLAKSIEDAERGNTIEVDL
ESYE
MAIVSYSIARKNFRSLIDKVNNDSDAVTITTNDSNAVLISESDYNAMMETLYLQQSPANAQHLAKSIEDAERGNTIEVDL
ESYE
Download Length: 255 bp
>AT120847 NZ_CP038242:70278-70532 [Staphylococcus warneri]
ATGGCAATAGTATCGTACTCAATAGCTAGAAAAAATTTTAGAAGTTTAATAGATAAAGTTAACAATGATTCAGATGCGGT
GACTATAACAACTAATGATAGCAATGCTGTACTGATTTCGGAGTCAGATTACAATGCGATGATGGAGACATTATACCTCC
AACAATCCCCTGCTAATGCCCAACACTTGGCTAAATCTATAGAAGATGCTGAGCGTGGAAATACAATAGAGGTAGATTTA
GAATCATATGAGTAG
ATGGCAATAGTATCGTACTCAATAGCTAGAAAAAATTTTAGAAGTTTAATAGATAAAGTTAACAATGATTCAGATGCGGT
GACTATAACAACTAATGATAGCAATGCTGTACTGATTTCGGAGTCAGATTACAATGCGATGATGGAGACATTATACCTCC
AACAATCCCCTGCTAATGCCCAACACTTGGCTAAATCTATAGAAGATGCTGAGCGTGGAAATACAATAGAGGTAGATTTA
GAATCATATGAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A364USX6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2T4PYE3 |