Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2428351..2428535 Replicon chromosome
Accession NZ_CP038229
Organism Staphylococcus aureus strain MJ163

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag E4J95_RS11980 Protein ID WP_000482647.1
Coordinates 2428428..2428535 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2428351..2428411 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4J95_RS11965 2423802..2423969 - 168 WP_001790576.1 hypothetical protein -
E4J95_RS11970 2424200..2425933 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
E4J95_RS11975 2425958..2427721 - 1764 WP_169449299.1 ABC transporter ATP-binding protein/permease -
- 2428351..2428411 + 61 - - Antitoxin
E4J95_RS11980 2428428..2428535 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
E4J95_RS11985 2428669..2429055 - 387 WP_000779360.1 flippase GtxA -
E4J95_RS11990 2429323..2430465 + 1143 WP_001176863.1 glycerate kinase -
E4J95_RS11995 2430525..2431184 + 660 WP_000831298.1 membrane protein -
E4J95_RS12000 2431366..2432577 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
E4J95_RS12005 2432700..2433173 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T120839 WP_000482647.1 NZ_CP038229:c2428535-2428428 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T120839 NZ_CP038229:c2428535-2428428 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT120839 NZ_CP038229:2428351-2428411 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References