Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2186732..2186949 Replicon chromosome
Accession NZ_CP038183
Organism Staphylococcus aureus strain MJ015

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E3306_RS10840 Protein ID WP_001802298.1
Coordinates 2186845..2186949 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2186732..2186787 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3306_RS10820 2182926..2183591 - 666 WP_001024095.1 SDR family oxidoreductase -
E3306_RS10825 2183743..2184063 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E3306_RS10830 2184065..2185045 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E3306_RS10835 2185311..2186402 + 1092 WP_000495683.1 hypothetical protein -
- 2186732..2186787 + 56 - - Antitoxin
E3306_RS10840 2186845..2186949 - 105 WP_001802298.1 hypothetical protein Toxin
E3306_RS10845 2187110..2187593 - 484 Protein_2095 recombinase family protein -
E3306_RS10850 2187636..2188772 - 1137 WP_000115564.1 SAP domain-containing protein -
E3306_RS10855 2189061..2189153 + 93 WP_001790138.1 hypothetical protein -
E3306_RS10860 2189858..2190715 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E3306_RS10865 2190783..2191565 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T120786 WP_001802298.1 NZ_CP038183:c2186949-2186845 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T120786 NZ_CP038183:c2186949-2186845 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT120786 NZ_CP038183:2186732-2186787 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References