Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2554810..2554994 Replicon chromosome
Accession NZ_CP038021
Organism Staphylococcus aureus strain 04-002

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag E3I93_RS13295 Protein ID WP_000482647.1
Coordinates 2554887..2554994 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2554810..2554870 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3I93_RS13270 2550320..2550487 - 168 Protein_2463 hypothetical protein -
E3I93_RS13280 2550718..2552451 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
E3I93_RS13285 2552476..2554239 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2554810..2554870 + 61 - - Antitoxin
E3I93_RS13295 2554887..2554994 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
E3I93_RS13300 2555128..2555514 - 387 WP_000779351.1 flippase GtxA -
E3I93_RS13305 2555782..2556924 + 1143 WP_001176855.1 glycerate kinase -
E3I93_RS13310 2556984..2557643 + 660 WP_000831298.1 membrane protein -
E3I93_RS13315 2557825..2559036 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
E3I93_RS13320 2559159..2559632 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T120667 WP_000482647.1 NZ_CP038021:c2554994-2554887 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T120667 NZ_CP038021:c2554994-2554887 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT120667 NZ_CP038021:2554810-2554870 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References