Detailed information of TA system TA120658

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1919342..1919522
• Replicon: chromosome
• Accession: NZ_CP038021
• Organism: Staphylococcus aureus strain 04-002

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3I93_RS09575
• Protein ID: WP_001801861.1
• Coordinates: 1919342..1919437 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1919465..1919522 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3I93_RS09540	1914487..1915113	+	627	WP_000669038.1	hypothetical protein	-
E3I93_RS09545	1915154..1915498	+	345	WP_000627550.1	DUF3969 family protein	-
E3I93_RS09550	1915596..1916168	+	573	WP_000414222.1	hypothetical protein	-
E3I93_RS09555	1916317..1917683	-	1367	Protein_1805	FRG domain-containing protein	-
E3I93_RS09560	1917683..1918252	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3I93_RS09565	1918445..1918891	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3I93_RS09575	1919342..1919437	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1919465..1919522	-	58	-	-	Antitoxin
E3I93_RS09580	1919560..1919661	+	102	WP_001791232.1	hypothetical protein	-
E3I93_RS09585	1919836..1920278	-	443	Protein_1810	DUF1433 domain-containing protein	-
E3I93_RS09590	1920283..1920720	-	438	WP_103149248.1	DUF1433 domain-containing protein	-
E3I93_RS09595	1920720..1921162	-	443	Protein_1812	DUF1433 domain-containing protein	-
E3I93_RS09600	1921687..1924106	+	2420	Protein_1813	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T120658 WP_001801861.1 NZ_CP038021:1919342-1919437 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T120658 NZ_CP038021:1919342-1919437 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT120658 NZ_CP038021:c1919522-1919465 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin