Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4581258..4581912 Replicon chromosome
Accession NZ_CP038001
Organism Pseudomonas sp. SXM-1

Toxin (Protein)


Gene name higB Uniprot ID A0A2N7Y400
Locus tag DCC84_RS21660 Protein ID WP_032899042.1
Coordinates 4581258..4581608 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A829MR32
Locus tag DCC84_RS21665 Protein ID WP_003219555.1
Coordinates 4581598..4581912 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCC84_RS21650 4578016..4579548 + 1533 WP_003219558.1 NADH-quinone oxidoreductase subunit M -
DCC84_RS21655 4579556..4581019 + 1464 WP_003219557.1 NADH-quinone oxidoreductase subunit NuoN -
DCC84_RS21660 4581258..4581608 + 351 WP_032899042.1 toxin Toxin
DCC84_RS21665 4581598..4581912 + 315 WP_003219555.1 transcriptional regulator Antitoxin
DCC84_RS21670 4581972..4583651 - 1680 WP_134326934.1 methyl-accepting chemotaxis protein -
DCC84_RS21675 4583722..4585041 - 1320 WP_161635727.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13771.62 Da        Isoelectric Point: 9.9312

>T120633 WP_032899042.1 NZ_CP038001:4581258-4581608 [Pseudomonas sp. SXM-1]
MDALFIELPAFERHRRDYLSDELFHGFQQELMRNPQAGNVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLSAQHKTALKHLLDREIKARKSYET

Download         Length: 351 bp

>T120633 NZ_CP038001:4581258-4581608 [Pseudomonas sp. SXM-1]
ATGGATGCTCTATTTATCGAATTGCCGGCCTTTGAGCGGCACCGCAGGGATTATCTGAGTGATGAGTTATTTCACGGCTT
TCAACAAGAGTTGATGAGAAACCCGCAAGCGGGCAACGTGATAGAGGGAACCGGCGGGTTACGCAAGGTGCGCTTTGTCG
ACGAGCGACGCAACAAGGGCAAACGGGGTGGCCTGCGAGTCATCTATTACTGGTGGTCGGGCGGTACGCAGTTCTGGCTG
TTCACCCTTTATGGCAAACACGAACAGGACGACCTGAGCGCTCAACACAAAACGGCGCTCAAACACCTGCTGGACAGGGA
AATCAAAGCGAGAAAATCTTATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11770.54 Da        Isoelectric Point: 9.9187

>AT120633 WP_003219555.1 NZ_CP038001:4581598-4581912 [Pseudomonas sp. SXM-1]
MKRDIFSELVEGFDALADEREGKVTLRSHKVQLSKLAPLTADEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQAATLIRLVSKFPETVERLALLT

Download         Length: 315 bp

>AT120633 NZ_CP038001:4581598-4581912 [Pseudomonas sp. SXM-1]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGCTTCGACGCGCTGGCAGATGAACGAGAAGGCAAGGTAACGCTGCG
CAGCCACAAGGTGCAGTTGAGCAAGCTGGCACCGCTCACTGCCGACGAAGTAGTCGCTGTGCGTCAACAACTCAATCTGT
CGCGCTCGGTGTTTGCGATGTACCTGCGCACCAACACCCGGACCCTGGAAAATTGGGAGCAAGGCCGGGCCACACCCAAT
GCTCAGGCGGCAACCTTGATTCGGCTGGTGTCGAAGTTTCCGGAGACGGTGGAACGTTTGGCGCTGTTGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N7Y400

Antitoxin

Source ID Structure
AlphaFold DB A0A829MR32

References