Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 402757..403270 Replicon chromosome
Accession NZ_CP037954
Organism Chryseobacterium sp. NBC 122 strain NBC122

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NBC122_RS01925 Protein ID WP_133438753.1
Coordinates 402757..403014 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NBC122_RS01930 Protein ID WP_133438754.1
Coordinates 403016..403270 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBC122_RS01900 398427..398882 - 456 WP_133438748.1 Lrp/AsnC family transcriptional regulator -
NBC122_RS01905 399040..400245 + 1206 WP_133438749.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
NBC122_RS01910 400378..400878 - 501 WP_133438750.1 5-(carboxyamino)imidazole ribonucleotide mutase -
NBC122_RS01915 400924..402120 - 1197 WP_133438751.1 TIGR03862 family flavoprotein -
NBC122_RS01920 402179..402652 - 474 WP_133438752.1 CYTH domain-containing protein -
NBC122_RS01925 402757..403014 - 258 WP_133438753.1 Txe/YoeB family addiction module toxin Toxin
NBC122_RS01930 403016..403270 - 255 WP_133438754.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NBC122_RS01935 403506..404405 + 900 WP_133438755.1 EamA family transporter -
NBC122_RS01940 404585..405313 - 729 WP_133438756.1 ABC transporter substrate-binding protein -
NBC122_RS01945 405319..406638 - 1320 WP_133438757.1 magnesium transporter -
NBC122_RS01950 407040..407669 + 630 WP_133438758.1 CoA pyrophosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10585.19 Da        Isoelectric Point: 8.7937

>T120563 WP_133438753.1 NZ_CP037954:c403014-402757 [Chryseobacterium sp. NBC 122]
MKYIFVDESWEDYLYWQKIDKKKLKRINDLLKDISRTPFEGIGKPEPLKHKYAGFWSRRIDDEHRLIYKFQEDDILIAKC
RFHYD

Download         Length: 258 bp

>T120563 NZ_CP037954:c403014-402757 [Chryseobacterium sp. NBC 122]
ATGAAATATATTTTCGTGGATGAATCCTGGGAGGATTATTTGTACTGGCAAAAAATCGATAAGAAAAAACTGAAACGGAT
AAATGATTTGTTAAAGGATATTTCACGAACTCCTTTTGAAGGCATCGGAAAGCCAGAACCGCTGAAACACAAATACGCTG
GATTTTGGTCGAGAAGAATCGATGATGAACACCGCTTGATTTATAAATTTCAAGAAGATGATATCTTGATTGCTAAGTGT
AGATTTCATTATGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9706.09 Da        Isoelectric Point: 6.3586

>AT120563 WP_133438754.1 NZ_CP037954:c403270-403016 [Chryseobacterium sp. NBC 122]
MFITSVSDFRKDIKSYLDRVSKNFETLIINRGKDSGIVVMSLEEYNSLMATNYELSSRKNEMRLDAAIEKLKSGKSYSKE
LIEE

Download         Length: 255 bp

>AT120563 NZ_CP037954:c403270-403016 [Chryseobacterium sp. NBC 122]
ATGTTTATCACTAGTGTTTCTGATTTTAGAAAAGATATCAAATCCTATTTAGACCGCGTTTCAAAAAACTTTGAAACCTT
GATCATTAATCGTGGCAAAGATTCTGGAATCGTTGTAATGTCCTTGGAAGAATACAATTCTTTGATGGCAACCAATTACG
AGCTGTCTTCGCGTAAGAATGAGATGCGATTAGATGCTGCCATCGAGAAATTGAAAAGTGGAAAATCTTATTCTAAGGAA
TTAATCGAAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References