Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4467856..4468711 Replicon chromosome
Accession NZ_CP037950
Organism Erwinia sp. QL-Z3

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag E2F51_RS21485 Protein ID WP_134824518.1
Coordinates 4467856..4468344 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag E2F51_RS21490 Protein ID WP_134824519.1
Coordinates 4468370..4468711 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2F51_RS21455 4463091..4463567 - 477 WP_134824514.1 nuclear transport factor 2 family protein -
E2F51_RS21460 4463627..4464196 - 570 WP_134824943.1 TetR family transcriptional regulator -
E2F51_RS21465 4464271..4464756 + 486 WP_134824515.1 GNAT family N-acetyltransferase -
E2F51_RS21470 4464824..4465840 - 1017 WP_134824516.1 NADP-dependent oxidoreductase -
E2F51_RS21475 4465930..4466832 + 903 WP_134824944.1 LysR family transcriptional regulator -
E2F51_RS21480 4466944..4467684 - 741 WP_134824517.1 SDR family oxidoreductase -
E2F51_RS21485 4467856..4468344 - 489 WP_134824518.1 type II toxin-antitoxin system YhaV family toxin Toxin
E2F51_RS21490 4468370..4468711 - 342 WP_134824519.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
E2F51_RS21495 4468863..4469510 - 648 WP_134824520.1 DUF1028 domain-containing protein -
E2F51_RS21500 4469632..4471218 + 1587 WP_134824521.1 ABC transporter substrate-binding protein -
E2F51_RS21505 4471239..4472186 + 948 WP_134824522.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(13-112)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 19163.03 Da        Isoelectric Point: 9.8197

>T120542 WP_134824518.1 NZ_CP037950:c4468344-4467856 [Erwinia sp. QL-Z3]
MEYLEINGWKFYFHSCFLTQLAELQNKVLALKKKDPQGYHKKKETKLLAAIEQIITRVIPANPLDSHFRQGNTLGQDYRH
WYRVKFLQQFRLFFRFSVPHRTIIIGWVNDFGTLSAYGSKTDAYTVFERMLKSGEPPDDWEALLKHCQTDARVINSDISR
KY

Download         Length: 489 bp

>T120542 NZ_CP037950:c4468344-4467856 [Erwinia sp. QL-Z3]
ATGGAGTATTTGGAGATCAATGGATGGAAATTCTATTTTCATTCCTGTTTTCTGACGCAGCTGGCTGAACTTCAAAATAA
GGTCCTGGCGCTGAAAAAAAAGGATCCCCAGGGCTATCACAAAAAGAAAGAAACCAAGCTGCTGGCGGCGATTGAGCAAA
TCATTACTCGGGTGATCCCGGCCAATCCACTGGACAGCCACTTTCGGCAGGGCAATACCTTAGGCCAGGATTACCGGCAC
TGGTACCGCGTCAAATTCCTGCAGCAATTTCGGTTATTCTTCCGCTTCAGCGTGCCCCACAGAACCATCATTATTGGTTG
GGTAAATGATTTCGGCACGCTTAGCGCTTATGGTTCGAAAACAGATGCCTATACGGTATTTGAACGGATGCTGAAGTCTG
GCGAACCCCCTGATGATTGGGAGGCGCTGCTGAAGCATTGCCAAACCGATGCCAGGGTTATAAACAGCGATATTTCTCGG
AAATATTAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12628.24 Da        Isoelectric Point: 4.1675

>AT120542 WP_134824519.1 NZ_CP037950:c4468711-4468370 [Erwinia sp. QL-Z3]
MNVNMADVSLRAESRLTERSQTTIPAAIRDALQLKPGEFIEYALLPGGKVVMSRREEEEAEDPVVPQFLAFLENDMMTNP
HHIHAVPREFWAGIQQLTAGVEVDLDGPLTDDE

Download         Length: 342 bp

>AT120542 NZ_CP037950:c4468711-4468370 [Erwinia sp. QL-Z3]
ATGAATGTAAACATGGCAGACGTGTCTTTGCGCGCGGAGTCCCGACTCACTGAGCGCAGCCAGACCACCATTCCCGCAGC
GATTCGCGATGCGCTGCAACTGAAGCCGGGAGAATTCATTGAATACGCTCTGCTGCCCGGCGGTAAAGTCGTTATGTCCC
GACGAGAAGAAGAAGAAGCGGAAGATCCGGTGGTCCCGCAGTTTCTGGCTTTCCTCGAAAACGACATGATGACCAACCCG
CATCATATCCATGCAGTGCCACGCGAATTTTGGGCAGGGATCCAGCAACTGACTGCTGGCGTTGAGGTCGATTTAGACGG
GCCGCTGACTGACGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References