Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 2864077..2864335 | Replicon | chromosome |
Accession | NZ_CP037449 | ||
Organism | Escherichia coli strain ATCC 25922 |
Toxin (Protein)
Gene name | hokC | Uniprot ID | S1NX00 |
Locus tag | E0708_RS13425 | Protein ID | WP_000809168.1 |
Coordinates | 2864077..2864229 (-) | Length | 51 a.a. |
Antitoxin (RNA)
Gene name | sokC | ||
Locus tag | - | ||
Coordinates | 2864278..2864335 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E0708_RS13405 | 2859322..2860035 | - | 714 | WP_001102391.1 | acidic protein MsyB | - |
E0708_RS13410 | 2860061..2860465 | - | 405 | WP_000843687.1 | DUF2541 family protein | - |
E0708_RS13415 | 2860837..2862753 | + | 1917 | WP_000516135.1 | molecular chaperone DnaK | - |
E0708_RS13420 | 2862842..2863972 | + | 1131 | WP_001118465.1 | molecular chaperone DnaJ | - |
E0708_RS13425 | 2864077..2864229 | - | 153 | WP_000809168.1 | type I toxin-antitoxin system toxin MokC | Toxin |
- | 2864278..2864335 | + | 58 | - | - | Antitoxin |
E0708_RS13430 | 2864844..2865605 | + | 762 | WP_001274832.1 | hypothetical protein | - |
E0708_RS13435 | 2865625..2867118 | + | 1494 | WP_001443162.1 | sulfatase-like hydrolase/transferase | - |
E0708_RS13440 | 2867247..2868506 | + | 1260 | WP_000494928.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5501.57 Da Isoelectric Point: 7.1312
>T119965 WP_000809168.1 NZ_CP037449:c2864229-2864077 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE
Download Length: 153 bp
>T119965 NZ_CP037449:c2864229-2864077 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTATTCACGGCTTACGAATCCGAGTAA
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTATTCACGGCTTACGAATCCGAGTAA
Antitoxin
Download Length: 58 bp
>AT119965 NZ_CP037449:2864278-2864335 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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