Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 3437621..3438279 Replicon chromosome
Accession NZ_CP036532
Organism Roseitalea porphyridii strain MA7-20

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag E0E05_RS16825 Protein ID WP_131617743.1
Coordinates 3437923..3438279 (-) Length 119 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag E0E05_RS16820 Protein ID WP_131617742.1
Coordinates 3437621..3437905 (-) Length 95 a.a.

Genomic Context

E0E05_RS16810E0E05_RS16815E0E05_RS16830E0E05_RS16835E0E05_RS16840E0E05_RS16845E0E05_RS16855E0E05_RS16805E0E05_RS16820E0E05_RS16825E0E05_RS16850
Location: 3436326..3436940 (615 bp)
Type: Others
Protein ID: WP_131617740.1
Location: 3436937..3437602 (666 bp)
Type: Others
Protein ID: WP_131617741.1
Location: 3438361..3438825 (465 bp)
Type: Others
Protein ID: WP_131617744.1
Location: 3438895..3439680 (786 bp)
Type: Others
Protein ID: WP_131617745.1
Location: 3439685..3439858 (174 bp)
Type: Others
Protein ID: WP_131617746.1
Location: 3439855..3440472 (618 bp)
Type: Others
Protein ID: WP_131617747.1
Location: 3441800..3442177 (378 bp)
Type: Others
Protein ID: WP_131617749.1
Location: 3433413..3436106 (2694 bp)
Type: Others
Protein ID: WP_131617739.1
Location: 3437621..3437905 (285 bp)
Type: Antitoxin
Protein ID: WP_131617742.1
Location: 3437923..3438279 (357 bp)
Type: Toxin
Protein ID: WP_131617743.1
Location: 3440490..3441734 (1245 bp)
Type: Others
Protein ID: WP_131617748.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E0E05_RS168053433413..3436106-2694WP_131617739.1aconitate hydratase AcnA-
E0E05_RS168103436326..3436940+615WP_131617740.1heme ABC exporter ATP-binding protein CcmA-
E0E05_RS168153436937..3437602+666WP_131617741.1heme exporter protein CcmB-
E0E05_RS168203437621..3437905-285WP_131617742.1helix-turn-helix domain-containing proteinAntitoxin
E0E05_RS168253437923..3438279-357WP_131617743.1type II toxin-antitoxin system RelE/ParE family toxinToxin
E0E05_RS168303438361..3438825+465WP_131617744.1hypothetical protein-
E0E05_RS168353438895..3439680+786WP_131617745.1heme ABC transporter permease-
E0E05_RS168403439685..3439858+174WP_131617746.1heme exporter protein CcmD-
E0E05_RS168453439855..3440472+618WP_131617747.1DsbE family thiol:disulfide interchange protein-
E0E05_RS168503440490..3441734-1245WP_131617748.1MFS transporter-
E0E05_RS168553441800..3442177+378WP_131617749.1YggT family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(38-87)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12511.26 Da        Isoelectric Point: 10.6179

>T119942 WP_131617743.1 NZ_CP036532:c3438279-3437923 [Roseitalea porphyridii]
MHTVVTTSVFERHAKAAGLSEEELSGIIAYLADNPKAGSVIPGTGGARKVRFAGAGKGKRGGYRTIHYFAADDVPIFLLA
LVKKGDRADISQAERDALAATLPRIAEAYRTGSGARRR

Download         Length: 357 bp

>T119942 NZ_CP036532:c3438279-3437923 [Roseitalea porphyridii]
ATGCACACGGTTGTCACGACGTCGGTCTTCGAGCGGCACGCAAAGGCGGCTGGCCTTTCCGAAGAGGAGTTGAGCGGCAT
CATTGCATATCTTGCCGACAACCCGAAAGCGGGATCGGTGATTCCTGGGACAGGCGGTGCGCGGAAAGTGCGCTTTGCGG
GCGCCGGCAAGGGCAAGCGCGGTGGTTACCGCACGATCCACTATTTCGCGGCCGATGACGTGCCGATTTTCCTGCTGGCG
CTCGTCAAGAAGGGCGACAGAGCCGATATCAGCCAGGCCGAGCGTGACGCGCTTGCCGCGACCTTGCCCAGGATCGCGGA
GGCATACCGGACAGGGTCGGGCGCCAGAAGAAGATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10383.93 Da        Isoelectric Point: 10.3413

>AT119942 WP_131617742.1 NZ_CP036532:c3437905-3437621 [Roseitalea porphyridii]
MSKFGRELVESAEEALAIAKAEKAPSRMVVPAKTDVAALRRRLGLTQAGFAARYGLNVATVRDWEQNRRQPDQPARVLLK
VIENDPEAVERALA

Download         Length: 285 bp

>AT119942 NZ_CP036532:c3437905-3437621 [Roseitalea porphyridii]
ATGAGCAAGTTTGGCCGGGAACTGGTCGAGAGCGCCGAGGAAGCATTGGCCATCGCCAAGGCCGAAAAGGCCCCATCCCG
CATGGTCGTACCCGCCAAGACCGACGTGGCCGCGTTGCGGCGGCGCCTCGGGCTGACGCAGGCCGGCTTTGCCGCCCGCT
ATGGCCTGAACGTTGCCACCGTCCGTGACTGGGAACAGAACCGCCGGCAACCCGACCAGCCGGCCCGCGTGCTGCTGAAG
GTCATCGAAAACGATCCGGAAGCCGTCGAGCGGGCGCTCGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References