Detailed information of TA system TA119890

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 2598555..2599123
• Replicon: chromosome
• Accession: NZ_CP036498
• Organism: Rhodopseudomonas sp. SK50-23

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: RPMA_RS12125
• Protein ID: WP_211913030.1
• Coordinates: 2598857..2599123 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: RPMA_RS12120
• Protein ID: WP_249225645.1
• Coordinates: 2598555..2598860 (+)
• Length: 102 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RPMA_RS12105 (RPMA_12045)	2594493..2594681	-	189	WP_211913027.1	hypothetical protein	-
RPMA_RS12110 (RPMA_12050)	2595142..2596470	+	1329	WP_211913028.1	hypothetical protein	-
RPMA_RS12115 (RPMA_12055)	2596478..2597314	+	837	WP_211913029.1	hypothetical protein	-
RPMA_RS12120 (RPMA_12060)	2598555..2598860	+	306	WP_249225645.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
RPMA_RS12125 (RPMA_12065)	2598857..2599123	+	267	WP_211913030.1	Txe/YoeB family addiction module toxin	Toxin
RPMA_RS12130 (RPMA_12070)	2599193..2600377	-	1185	WP_211913031.1	MFS transporter	-
RPMA_RS12135 (RPMA_12075)	2600672..2601046	+	375	WP_211913032.1	hypothetical protein	-
RPMA_RS12140 (RPMA_12080)	2601067..2602299	-	1233	WP_211913624.1	polysaccharide deacetylase family protein	-
RPMA_RS12145 (RPMA_12085)	2602490..2603260	-	771	WP_249225646.1	polysaccharide deacetylase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (13-86)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10497.95 Da
• Isoelectric Point: 9.4833

>T119890 WP_211913030.1 NZ_CP036498:2598857-2599123 [Rhodopseudomonas sp. SK50-23]
MKTAWTEDAWADYLSWQQEDQKVLQAINALIKDIKRDPFRGLGKPEPLKHTLQGWWSRRITGEHRLVYRVTGKGETQQLD
IVQCRYHY

Nucleotide

• Length: 267 bp

>T119890 NZ_CP036498:2598857-2599123 [Rhodopseudomonas sp. SK50-23]
ATGAAAACGGCTTGGACCGAAGATGCCTGGGCGGATTATCTGAGTTGGCAGCAGGAGGACCAGAAAGTCCTCCAGGCCAT
CAATGCACTTATCAAGGACATCAAGCGTGATCCGTTTAGGGGGCTCGGGAAACCGGAGCCCCTTAAACATACGCTGCAGG
GTTGGTGGTCGCGCCGGATCACAGGCGAGCACCGTCTGGTCTATCGCGTCACCGGCAAAGGCGAAACGCAGCAGCTCGAT
ATCGTGCAGTGTCGATATCACTACTGA

Antitoxin

Protein

• Length: 102 a.a.
• Molecular weight: 11434.86 Da
• Isoelectric Point: 4.4652

>AT119890 WP_249225645.1 NZ_CP036498:2598555-2598860 [Rhodopseudomonas sp. SK50-23]
MYNVVVDPMERDMGHVSYSELRSNLASYMDEVCDDRTALVVTRQNARSVVLMSEEEYEGLMETFHLLKSPANATRLLRSI
DEANRGELTPRETLEPPSAGK

Nucleotide

• Length: 306 bp

>AT119890 NZ_CP036498:2598555-2598860 [Rhodopseudomonas sp. SK50-23]
ATGTACAATGTGGTCGTCGATCCGATGGAGCGCGATATGGGGCATGTTTCCTACAGTGAGCTGCGCAGCAACCTGGCCTC
CTACATGGACGAAGTTTGCGATGATCGGACAGCGCTGGTGGTGACACGCCAGAACGCGCGGAGCGTCGTGCTGATGTCTG
AAGAGGAATATGAGGGGTTGATGGAGACGTTTCATCTCCTGAAAAGCCCGGCCAATGCCACGCGCTTGCTGCGCTCGATC
GATGAGGCCAATCGGGGCGAGCTCACGCCGCGGGAGACGCTTGAGCCGCCGTCCGCTGGCAAATGA