Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 4467375..4467976 Replicon chromosome
Accession NZ_CP036495
Organism Pseudomonas viridiflava strain Psy35

Toxin (Protein)


Gene name higB Uniprot ID A0A5E6ZPL8
Locus tag EZZ81_RS19890 Protein ID WP_029241687.1
Coordinates 4467375..4467689 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EZZ81_RS19895 Protein ID WP_029241688.1
Coordinates 4467689..4467976 (+) Length 96 a.a.

Genomic Context

EZZ81_RS19880EZZ81_RS19890EZZ81_RS19895EZZ81_RS19900EZZ81_RS19905EZZ81_RS19910EZZ81_RS19915EZZ81_RS19920EZZ81_RS19885EZZ81_RS19925
Location: 4463798..4465129 (1332 bp)
Type: Others
Protein ID: WP_029241685.1
Location: 4467375..4467689 (315 bp)
Type: Toxin
Protein ID: WP_029241687.1
Location: 4467689..4467976 (288 bp)
Type: Antitoxin
Protein ID: WP_029241688.1
Location: 4468132..4469475 (1344 bp)
Type: Others
Protein ID: WP_004879110.1
Location: 4469580..4470023 (444 bp)
Type: Others
Protein ID: WP_029241689.1
Location: 4470115..4470825 (711 bp)
Type: Others
Protein ID: WP_029241690.1
Location: 4470895..4471356 (462 bp)
Type: Others
Protein ID: WP_029241691.1
Location: 4471366..4472073 (708 bp)
Type: Others
Protein ID: WP_029241692.1
Location: 4465211..4467106 (1896 bp)
Type: Others
Protein ID: WP_029241686.1
Location: 4472122..4472901 (780 bp)
Type: Others
Protein ID: WP_002554680.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EZZ81_RS19880 (EZZ81_20155)4463798..4465129+1332WP_029241685.1AcvB/VirJ family lysyl-phosphatidylglycerol hydrolase-
EZZ81_RS19885 (EZZ81_20160)4465211..4467106-1896WP_029241686.1potassium transporter Kup-
EZZ81_RS19890 (EZZ81_20165)4467375..4467689+315WP_029241687.1hypothetical proteinToxin
EZZ81_RS19895 (EZZ81_20170)4467689..4467976+288WP_029241688.1helix-turn-helix domain-containing proteinAntitoxin
EZZ81_RS19900 (EZZ81_20175)4468132..4469475+1344WP_004879110.130S ribosomal protein S12 methylthiotransferase RimO-
EZZ81_RS19905 (EZZ81_20180)4469580..4470023+444WP_029241689.1GNAT family N-acetyltransferase-
EZZ81_RS19910 (EZZ81_20185)4470115..4470825+711WP_029241690.1rRNA pseudouridine synthase-
EZZ81_RS19915 (EZZ81_20190)4470895..4471356+462WP_029241691.1DUF1456 family protein-
EZZ81_RS19920 (EZZ81_20195)4471366..4472073+708WP_029241692.1tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO-
EZZ81_RS19925 (EZZ81_20200)4472122..4472901-780WP_002554680.1ferredoxin-NADP reductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11897.75 Da        Isoelectric Point: 10.7948

>T119884 WP_029241687.1 NZ_CP036495:4467375-4467689 [Pseudomonas viridiflava]
MIFIETPIFTSELRTHLSDDEYRALQSHLASQPEAGALIEDTGGLRKVRWTAHGKGKSGGVRVIYYHLSSANQIRMLLIY
RKGIMDSLTAKQKTQLRAINRRWK

Download         Length: 315 bp

>T119884 NZ_CP036495:4467375-4467689 [Pseudomonas viridiflava]
ATGATTTTTATCGAAACACCTATATTCACTTCAGAGCTCAGGACTCATCTGAGCGACGACGAATATCGCGCGCTTCAATC
GCACCTCGCATCCCAGCCGGAAGCTGGCGCGCTGATTGAAGACACAGGAGGATTGAGGAAGGTACGCTGGACTGCGCATG
GGAAAGGCAAGAGTGGTGGGGTAAGGGTGATTTATTACCACTTATCCTCTGCCAATCAGATACGAATGCTTTTGATCTAT
CGAAAAGGGATCATGGATTCCCTGACTGCGAAGCAAAAGACACAGCTGCGAGCAATCAACAGAAGGTGGAAATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10919.38 Da        Isoelectric Point: 7.3222

>AT119884 WP_029241688.1 NZ_CP036495:4467689-4467976 [Pseudomonas viridiflava]
MEKNLFDRLVESMTQMDEIDRDERQPSREFHVDAVQVKKIRQATGLSQASFAKRIDVAVGTLRNWEQGRREPEGPARALL
KAIHNDPEHVLAALR

Download         Length: 288 bp

>AT119884 NZ_CP036495:4467689-4467976 [Pseudomonas viridiflava]
ATGGAAAAGAATCTTTTTGATCGTCTTGTGGAAAGCATGACGCAAATGGACGAAATTGATCGCGATGAGCGCCAGCCTTC
CCGCGAGTTCCACGTTGATGCAGTTCAGGTAAAGAAGATCCGCCAGGCTACAGGGCTATCCCAGGCGAGCTTCGCCAAAC
GCATAGACGTGGCGGTAGGTACGCTTAGGAACTGGGAGCAAGGTCGCCGCGAACCTGAGGGGCCTGCCAGAGCCTTGTTA
AAGGCCATACACAACGACCCGGAACACGTATTGGCGGCGCTTCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A5E6ZPL8

Antitoxin

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Source
ID
Structure
No matching records found

References