Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 18312..18840 Replicon plasmid pZM36o
Accession NZ_CP036464
Organism Zymomonas mobilis strain ZM4*

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag EWS79_RS09475 Protein ID WP_062339761.1
Coordinates 18312..18581 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag EWS79_RS09480 Protein ID WP_062339759.1
Coordinates 18583..18840 (-) Length 86 a.a.

Genomic Context

EWS79_RS09440EWS79_RS09485EWS79_RS09490EWS79_RS09445EWS79_RS09450EWS79_RS09455EWS79_RS09460EWS79_RS09465EWS79_RS09470EWS79_RS09475EWS79_RS09480EWS79_RS09495EWS79_RS09500EWS79_RS09505EWS79_RS09510
Location: 13790..14773 (984 bp)
Type: Others
Protein ID: WP_062339740.1
Location: 19254..20522 (1269 bp)
Type: Others
Protein ID: WP_081094489.1
Location: 20769..21650 (882 bp)
Type: Others
Protein ID: WP_185761977.1
Location: 15097..15459 (363 bp)
Type: Others
Protein ID: WP_108125223.1
Location: 15995..16234 (240 bp)
Type: Others
Protein ID: WP_062339772.1
Location: 16245..16433 (189 bp)
Type: Others
Protein ID: WP_062339770.1
Location: 16912..17238 (327 bp)
Type: Others
Protein ID: WP_062339766.1
Location: 17343..17669 (327 bp)
Type: Others
Protein ID: WP_062339764.1
Location: 17698..18060 (363 bp)
Type: Others
Protein ID: WP_151457906.1
Location: 18312..18581 (270 bp)
Type: Toxin
Protein ID: WP_062339761.1
Location: 18583..18840 (258 bp)
Type: Antitoxin
Protein ID: WP_062339759.1
Location: 21721..21975 (255 bp)
Type: Others
Protein ID: WP_062339701.1
Location: 21981..22442 (462 bp)
Type: Others
Protein ID: WP_063630121.1
Location: 22456..22791 (336 bp)
Type: Others
Protein ID: WP_081094484.1
Location: 23038..23508 (471 bp)
Type: Others
Protein ID: WP_062339703.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EWS79_RS0944013790..14773+984WP_062339740.1hypothetical protein-
EWS79_RS0944515097..15459-363WP_108125223.1hypothetical protein-
EWS79_RS0945015995..16234-240WP_062339772.1hypothetical protein-
EWS79_RS0945516245..16433-189WP_062339770.1hypothetical protein-
EWS79_RS0946016912..17238-327WP_062339766.1hypothetical protein-
EWS79_RS0946517343..17669-327WP_062339764.1hypothetical protein-
EWS79_RS0947017698..18060-363WP_151457906.1hypothetical protein-
EWS79_RS0947518312..18581-270WP_062339761.1type II toxin-antitoxin system YafQ family toxinToxin
EWS79_RS0948018583..18840-258WP_062339759.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
EWS79_RS0948519254..20522+1269WP_081094489.1DNA damage-inducible protein D-
EWS79_RS0949020769..21650+882WP_185761977.1hypothetical protein-
EWS79_RS0949521721..21975-255WP_062339701.1hypothetical protein-
EWS79_RS0950021981..22442-462WP_063630121.1helix-turn-helix domain-containing protein-
EWS79_RS0950522456..22791-336WP_081094484.1type II toxin-antitoxin system RelE/ParE family toxin-
EWS79_RS0951023038..23508-471WP_062339703.1helix-turn-helix domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..3649836498


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10398.16 Da        Isoelectric Point: 10.0220

>T119854 WP_062339761.1 NZ_CP036464:c18581-18312 [Zymomonas mobilis]
VLTPIRSSKFKKDIKKLQKRGKDMEKLKKAILYLINEQALPPAYRSHVLSGDWSGYYDLHLEPDWLLLYKIADMELHLAR
TGSHSDVFK

Download         Length: 270 bp

>T119854 NZ_CP036464:c18581-18312 [Zymomonas mobilis]
GTGCTAACGCCTATCCGATCGAGCAAATTCAAGAAAGACATAAAAAAATTACAGAAGCGAGGTAAGGATATGGAAAAATT
AAAAAAAGCCATTCTTTACCTGATTAATGAACAAGCCTTACCACCAGCCTACCGAAGCCATGTTTTAAGTGGCGATTGGT
CGGGTTACTACGATTTGCATTTGGAACCTGACTGGCTCCTGCTCTATAAAATAGCTGATATGGAATTGCATCTAGCGCGA
ACAGGCAGCCATTCAGATGTTTTTAAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9372.01 Da        Isoelectric Point: 8.6589

>AT119854 WP_062339759.1 NZ_CP036464:c18840-18583 [Zymomonas mobilis]
MKADSVVRARIPTLTKEAAIKTLEQMGLSISDAIRLLMTKIANEQRLPFSVELPTVETKKAIIELENGKGKTFKNADALF
EDLGI

Download         Length: 258 bp

>AT119854 NZ_CP036464:c18840-18583 [Zymomonas mobilis]
ATGAAAGCAGATTCTGTTGTTAGAGCACGCATCCCAACCTTGACCAAGGAAGCCGCGATTAAAACTTTGGAGCAGATGGG
ACTTAGTATTTCTGATGCTATCCGGTTGCTTATGACTAAAATCGCCAATGAGCAACGTCTTCCCTTTTCTGTTGAATTAC
CAACGGTGGAAACCAAAAAAGCGATTATCGAATTGGAAAATGGAAAAGGTAAGACTTTTAAAAATGCAGATGCTCTGTTC
GAGGATTTAGGTATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References