Detailed information of TA system TA119854

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): DinJ-YafQ (relBE)/YafQ-RelB
• Location: 18312..18840
• Replicon: plasmid pZM36o
• Accession: NZ_CP036464
• Organism: Zymomonas mobilis strain ZM4*

Toxin (Protein)

• Gene name: yafQ
• Uniprot ID: -
• Locus tag: EWS79_RS09475
• Protein ID: WP_062339761.1
• Coordinates: 18312..18581 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: EWS79_RS09480
• Protein ID: WP_062339759.1
• Coordinates: 18583..18840 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EWS79_RS09440	13790..14773	+	984	WP_062339740.1	hypothetical protein	-
EWS79_RS09445	15097..15459	-	363	WP_108125223.1	hypothetical protein	-
EWS79_RS09450	15995..16234	-	240	WP_062339772.1	hypothetical protein	-
EWS79_RS09455	16245..16433	-	189	WP_062339770.1	hypothetical protein	-
EWS79_RS09460	16912..17238	-	327	WP_062339766.1	hypothetical protein	-
EWS79_RS09465	17343..17669	-	327	WP_062339764.1	hypothetical protein	-
EWS79_RS09470	17698..18060	-	363	WP_151457906.1	hypothetical protein	-
EWS79_RS09475	18312..18581	-	270	WP_062339761.1	type II toxin-antitoxin system YafQ family toxin	Toxin
EWS79_RS09480	18583..18840	-	258	WP_062339759.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
EWS79_RS09485	19254..20522	+	1269	WP_081094489.1	DNA damage-inducible protein D	-
EWS79_RS09490	20769..21650	+	882	WP_185761977.1	hypothetical protein	-
EWS79_RS09495	21721..21975	-	255	WP_062339701.1	hypothetical protein	-
EWS79_RS09500	21981..22442	-	462	WP_063630121.1	helix-turn-helix domain-containing protein	-
EWS79_RS09505	22456..22791	-	336	WP_081094484.1	type II toxin-antitoxin system RelE/ParE family toxin	-
EWS79_RS09510	23038..23508	-	471	WP_062339703.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..36498	36498

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (6-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10398.16 Da
• Isoelectric Point: 10.0220

>T119854 WP_062339761.1 NZ_CP036464:c18581-18312 [Zymomonas mobilis]
VLTPIRSSKFKKDIKKLQKRGKDMEKLKKAILYLINEQALPPAYRSHVLSGDWSGYYDLHLEPDWLLLYKIADMELHLAR
TGSHSDVFK

Nucleotide

• Length: 270 bp

>T119854 NZ_CP036464:c18581-18312 [Zymomonas mobilis]
GTGCTAACGCCTATCCGATCGAGCAAATTCAAGAAAGACATAAAAAAATTACAGAAGCGAGGTAAGGATATGGAAAAATT
AAAAAAAGCCATTCTTTACCTGATTAATGAACAAGCCTTACCACCAGCCTACCGAAGCCATGTTTTAAGTGGCGATTGGT
CGGGTTACTACGATTTGCATTTGGAACCTGACTGGCTCCTGCTCTATAAAATAGCTGATATGGAATTGCATCTAGCGCGA
ACAGGCAGCCATTCAGATGTTTTTAAGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9372.01 Da
• Isoelectric Point: 8.6589

>AT119854 WP_062339759.1 NZ_CP036464:c18840-18583 [Zymomonas mobilis]
MKADSVVRARIPTLTKEAAIKTLEQMGLSISDAIRLLMTKIANEQRLPFSVELPTVETKKAIIELENGKGKTFKNADALF
EDLGI

Nucleotide

• Length: 258 bp

>AT119854 NZ_CP036464:c18840-18583 [Zymomonas mobilis]
ATGAAAGCAGATTCTGTTGTTAGAGCACGCATCCCAACCTTGACCAAGGAAGCCGCGATTAAAACTTTGGAGCAGATGGG
ACTTAGTATTTCTGATGCTATCCGGTTGCTTATGACTAAAATCGCCAATGAGCAACGTCTTCCCTTTTCTGTTGAATTAC
CAACGGTGGAAACCAAAAAAGCGATTATCGAATTGGAAAATGGAAAAGGTAAGACTTTTAAAAATGCAGATGCTCTGTTC
GAGGATTTAGGTATTTAA