Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) TglT-TakA/AbiEii-AbiEi
Location 3281281..3282700 Replicon chromosome
Accession NZ_CP036402
Organism Egibacter rhizosphaerae strain EGI 80759

Toxin (Protein)


Gene name tglT Uniprot ID -
Locus tag ER308_RS15145 Protein ID WP_165492133.1
Coordinates 3281843..3282700 (+) Length 286 a.a.

Antitoxin (Protein)


Gene name takA Uniprot ID -
Locus tag ER308_RS15140 Protein ID WP_131155759.1
Coordinates 3281281..3281850 (+) Length 190 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ER308_RS22090 3276845..3277069 + 225 WP_205745643.1 DUF433 domain-containing protein -
ER308_RS15110 3277513..3277923 - 411 WP_131155753.1 type II toxin-antitoxin system VapC family toxin -
ER308_RS15115 3277920..3278150 - 231 WP_131155754.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
ER308_RS15120 3278309..3278941 - 633 WP_131155755.1 hypothetical protein -
ER308_RS15125 3278938..3279975 - 1038 WP_131155756.1 hypothetical protein -
ER308_RS15130 3280089..3280583 + 495 WP_131155757.1 hypothetical protein -
ER308_RS15135 3280965..3281150 + 186 WP_131155758.1 hypothetical protein -
ER308_RS15140 3281281..3281850 + 570 WP_131155759.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
ER308_RS15145 3281843..3282700 + 858 WP_165492133.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
ER308_RS15150 3282604..3283971 - 1368 WP_131155761.1 integrase core domain-containing protein -
ER308_RS15155 3283984..3284385 - 402 WP_131155762.1 hypothetical protein -
ER308_RS15160 3284389..3284601 - 213 WP_131155763.1 hypothetical protein -
ER308_RS15165 3284621..3284800 + 180 WP_131155764.1 hypothetical protein -
ER308_RS15170 3284812..3285183 - 372 WP_131155765.1 hypothetical protein -
ER308_RS15175 3285192..3285656 - 465 WP_131155766.1 helix-turn-helix domain-containing protein -
ER308_RS15180 3285833..3286207 - 375 WP_205745644.1 hypothetical protein -
ER308_RS15185 3286267..3286542 - 276 WP_205745645.1 type II toxin-antitoxin system prevent-host-death family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(52-256)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-55)


Sequences

Toxin        


Download         Length: 286 a.a.        Molecular weight: 31158.10 Da        Isoelectric Point: 5.5802

>T119742 WP_165492133.1 NZ_CP036402:3281843-3282700 [Egibacter rhizosphaerae]
MADGPPHNLRSLQDRLRNHTRETQLPFGRVQRLLGVLVVGEMLRGQDLDLGVVKGGSNLEARLGIAATRASSDLDIVRVQ
SIERLRDSMAEALEAGWHGFSGRIVDRGPIGAPVPDAYQPHRLEVKLEYRGQRGAGTITLEVAVEEIDALEHVDAVTSED
GQAIFDAVGLPLPGPLPALAQHQQIAQKLHACTAPDEGGWVNDRAHDLVDLQLAHRSYDGTLAEIRATCERLFAARRRHP
WPPKVTVRDGWSQRYAEESAGLDVCADVEDAVAWANDLVARIARA

Download         Length: 858 bp

>T119742 NZ_CP036402:3281843-3282700 [Egibacter rhizosphaerae]
ATGGCTGACGGCCCGCCCCACAACCTGCGATCCCTGCAGGACCGCCTGCGCAACCACACCCGGGAGACCCAGCTGCCGTT
CGGACGCGTGCAGCGGTTGCTGGGCGTCCTGGTGGTCGGTGAGATGCTGCGCGGCCAGGACCTCGACCTCGGGGTGGTCA
AGGGCGGCTCGAACCTGGAGGCGCGGCTGGGCATCGCGGCCACCCGCGCCTCCAGCGACCTCGACATCGTGCGGGTCCAA
TCGATCGAACGGCTCCGCGACTCGATGGCTGAGGCCCTCGAGGCCGGTTGGCACGGGTTCAGCGGCCGCATCGTCGACCG
CGGCCCGATCGGCGCGCCCGTGCCCGACGCCTACCAGCCGCACCGCTTGGAGGTGAAGCTTGAGTACCGAGGCCAGCGGG
GAGCCGGGACGATCACGCTCGAAGTCGCCGTCGAGGAGATCGACGCGCTCGAACACGTCGACGCCGTGACTAGCGAGGAC
GGCCAGGCCATCTTCGACGCCGTCGGACTGCCCCTGCCGGGACCTCTCCCCGCGCTGGCACAGCACCAGCAGATCGCCCA
GAAACTGCACGCTTGCACCGCCCCCGACGAGGGCGGATGGGTCAACGACCGCGCCCACGACCTCGTGGATCTGCAGCTCG
CGCACCGCAGCTACGACGGCACGCTCGCGGAGATCCGAGCGACCTGCGAGCGGCTGTTCGCCGCGCGCCGGCGCCACCCC
TGGCCCCCGAAGGTGACCGTCCGCGACGGCTGGTCACAGCGCTACGCTGAGGAGTCCGCCGGCCTGGACGTCTGCGCCGA
CGTTGAAGACGCCGTTGCCTGGGCCAACGACCTTGTCGCACGCATCGCCCGGGCATAA

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 20888.91 Da        Isoelectric Point: 7.5559

>AT119742 WP_131155759.1 NZ_CP036402:3281281-3281850 [Egibacter rhizosphaerae]
MPGATWRQLYDIALDHHGFVTTTAARAVGVDGAYLRQMTQRGTLEQVAYGLYRVPEVPVTEQTPYMEAVLWTGPDAALSH
DAVLALHGLASANPSVIRVVTPRRVRRRQRPPVPLRVIKRTIPADQLTHYFAIPSTTVARALMDCRDLIMRSRLVEGAEQ
ARGEGLLRDAELDAVFDALGLHEPAHHDG

Download         Length: 570 bp

>AT119742 NZ_CP036402:3281281-3281850 [Egibacter rhizosphaerae]
ATGCCCGGTGCGACATGGCGGCAGCTGTACGACATCGCTCTGGACCACCACGGCTTCGTGACCACGACCGCCGCGAGGGC
GGTGGGCGTGGATGGCGCCTACCTGCGGCAGATGACGCAGCGCGGGACACTCGAGCAGGTCGCCTACGGCCTGTACCGAG
TTCCGGAGGTGCCGGTCACCGAGCAGACACCGTACATGGAGGCGGTGCTGTGGACCGGGCCTGACGCGGCCTTGTCGCAC
GACGCCGTCCTGGCCCTGCACGGCCTGGCGTCCGCCAACCCATCGGTCATCCGGGTCGTGACGCCGCGGCGCGTCCGGAG
GCGCCAACGCCCACCAGTCCCGCTGCGGGTCATCAAGCGGACGATTCCGGCGGACCAGCTCACTCACTACTTTGCGATCC
CCTCGACCACGGTCGCCCGCGCGCTGATGGACTGCCGTGATCTGATCATGCGCTCACGGCTGGTCGAGGGCGCAGAGCAG
GCGCGAGGCGAGGGCTTGCTCCGCGACGCTGAGCTCGACGCCGTCTTCGATGCACTGGGCCTCCACGAACCGGCGCACCA
CGATGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References