Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2769516..2770020 Replicon chromosome
Accession NZ_CP036259
Organism Sporomusa termitida strain DSM 4440

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag SPTER_RS13100 Protein ID WP_144350791.1
Coordinates 2769763..2770020 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SPTER_RS13095 Protein ID WP_144350790.1
Coordinates 2769516..2769770 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SPTER_RS13065 2766168..2767004 - 837 WP_170233257.1 DUF1694 domain-containing protein -
SPTER_RS13070 2767446..2768084 + 639 WP_144350788.1 hypothetical protein -
SPTER_RS13075 2768262..2768408 - 147 WP_144352900.1 IS3 family transposase -
SPTER_RS13080 2768357..2768581 - 225 WP_144352901.1 DDE-type integrase/transposase/recombinase -
SPTER_RS13085 2768630..2768890 - 261 Protein_2568 DNA polymerase -
SPTER_RS13090 2769241..2769426 - 186 WP_144350789.1 hypothetical protein -
SPTER_RS13095 2769516..2769770 + 255 WP_144350790.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SPTER_RS13100 2769763..2770020 + 258 WP_144350791.1 Txe/YoeB family addiction module toxin Toxin
SPTER_RS13105 2770139..2771242 - 1104 WP_144350792.1 epoxyqueuosine reductase -
SPTER_RS13115 2771768..2772574 - 807 WP_170233258.1 alpha/beta hydrolase -
SPTER_RS13120 2772698..2773819 - 1122 WP_144350794.1 MBL fold metallo-hydrolase -
SPTER_RS13125 2774622..2774921 + 300 WP_144350795.1 type II toxin-antitoxin system Phd/YefM family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10452.92 Da        Isoelectric Point: 7.2748

>T119460 WP_144350791.1 NZ_CP036259:2769763-2770020 [Sporomusa termitida]
MIKVWDDDAWNDYLYWQDTDRKMVKKINALIKDIERTPFDGLGKPEPLKHTLSGFWSRRIDPEHRLIYRIRDDKLEIAQC
RYHYD

Download         Length: 258 bp

>T119460 NZ_CP036259:2769763-2770020 [Sporomusa termitida]
ATGATTAAAGTCTGGGACGATGATGCTTGGAACGATTACCTGTACTGGCAAGACACGGATCGAAAGATGGTAAAGAAAAT
CAATGCTCTCATCAAAGATATCGAACGAACTCCTTTCGATGGTCTCGGCAAACCAGAACCCTTAAAACATACGTTGTCAG
GTTTTTGGAGCCGCCGGATCGACCCCGAACACAGACTGATATACCGGATCAGAGACGATAAACTCGAAATTGCCCAATGC
CGCTATCATTATGATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9726.95 Da        Isoelectric Point: 7.9482

>AT119460 WP_144350790.1 NZ_CP036259:2769516-2769770 [Sporomusa termitida]
MIAANYSTVRENFKEYCDRANNDVETIFVTRKSGGNVVILSEAEYNNMIENLYIRSNKANYDRLTKSIERLNQGKGIKKE
LMND

Download         Length: 255 bp

>AT119460 NZ_CP036259:2769516-2769770 [Sporomusa termitida]
ATGATAGCAGCCAACTATAGCACCGTGAGAGAAAATTTCAAAGAGTATTGCGACAGGGCGAATAACGATGTAGAGACTAT
TTTTGTAACCCGCAAGAGCGGCGGCAACGTGGTTATCCTGTCGGAAGCTGAATACAATAACATGATCGAAAACCTATACA
TCCGCAGCAACAAAGCCAACTATGACCGGCTAACGAAATCCATTGAGCGATTGAATCAAGGCAAGGGCATCAAGAAGGAA
TTAATGAATGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References