Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 112399..112985 Replicon chromosome
Accession NZ_CP036256
Organism Xanthomonas oryzae strain BAI23

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag EYC57_RS00505 Protein ID WP_131076070.1
Coordinates 112399..112677 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EYC57_RS00510 Protein ID WP_053503948.1
Coordinates 112695..112985 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EYC57_RS00500 110040..112301 + 2262 WP_131074206.1 exodeoxyribonuclease V subunit alpha -
EYC57_RS00505 112399..112677 + 279 WP_131076070.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EYC57_RS00510 112695..112985 + 291 WP_053503948.1 HigA family addiction module antidote protein Antitoxin
EYC57_RS00520 113934..115328 + 1395 WP_131076071.1 nucleoside hydrolase -
EYC57_RS00530 115778..116110 - 333 WP_003482333.1 hypothetical protein -
EYC57_RS00540 116446..116691 + 246 WP_024743556.1 hypothetical protein -
EYC57_RS00545 116807..117079 + 273 Protein_94 PAAR domain-containing protein -
EYC57_RS00555 117284..117586 + 303 WP_131074207.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(13-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10843.50 Da        Isoelectric Point: 9.3215

>T119458 WP_131076070.1 NZ_CP036256:112399-112677 [Xanthomonas oryzae]
ISSVIDKDAEKIRLGERSRRLPAESQMVARRKLRMLDAAAHPEDLRIPPANRLEALKGQWRGQCSIRINDQWRICFRWME
GDVFQVEIVDYH

Download         Length: 279 bp

>T119458 NZ_CP036256:112399-112677 [Xanthomonas oryzae]
ATCAGCAGCGTTATCGACAAGGACGCTGAAAAGATCCGGCTGGGTGAGCGTTCCCGCCGATTGCCGGCCGAGAGTCAGAT
GGTGGCGCGCCGCAAGTTGCGCATGCTCGATGCCGCCGCGCATCCCGAAGATCTGCGGATTCCGCCCGCCAACCGGCTGG
AAGCGTTGAAGGGCCAGTGGCGCGGCCAGTGCAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATGGAA
GGCGATGTGTTCCAAGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10345.95 Da        Isoelectric Point: 6.4654

>AT119458 WP_053503948.1 NZ_CP036256:112695-112985 [Xanthomonas oryzae]
MTVLANIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT119458 NZ_CP036256:112695-112985 [Xanthomonas oryzae]
ATGACAGTCCTAGCCAATATCCACCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGCATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTTGGCCTGCAGGCCGATGACGAACTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References