Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5144051..5144637 Replicon chromosome
Accession NZ_CP036255
Organism Xanthomonas oryzae strain BB151-3

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag EYC56_RS24140 Protein ID WP_131086131.1
Coordinates 5144359..5144637 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EYC56_RS24135 Protein ID WP_053503948.1
Coordinates 5144051..5144341 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EYC56_RS24095 5139316..5139792 - 477 WP_053501997.1 DUF4123 domain-containing protein -
EYC56_RS24100 5139795..5140229 - 435 WP_131085566.1 PAAR domain-containing protein -
EYC56_RS24105 5140345..5140590 - 246 WP_024743556.1 hypothetical protein -
EYC56_RS24115 5140926..5141258 + 333 WP_003482333.1 hypothetical protein -
EYC56_RS24125 5141708..5143102 - 1395 WP_053503949.1 nucleoside hydrolase -
EYC56_RS24135 5144051..5144341 - 291 WP_053503948.1 HigA family addiction module antidote protein Antitoxin
EYC56_RS24140 5144359..5144637 - 279 WP_131086131.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EYC56_RS24145 5144735..5146996 - 2262 WP_131085822.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(13-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10809.48 Da        Isoelectric Point: 9.3215

>T119457 WP_131086131.1 NZ_CP036255:c5144637-5144359 [Xanthomonas oryzae]
ISSVIDKDAEKIRLGERSRRLPAESQMVARRKLRMLDAAAHPEDLRIPPANRLEALKGQWRGQCSIRINDQWRICFRWME
GDVLQVEIVDYH

Download         Length: 279 bp

>T119457 NZ_CP036255:c5144637-5144359 [Xanthomonas oryzae]
ATCAGCAGCGTTATCGACAAGGACGCTGAAAAGATCCGGCTGGGTGAGCGTTCCCGCCGATTGCCGGCCGAGAGTCAGAT
GGTGGCGCGCCGCAAGTTGCGCATGCTCGATGCCGCCGCGCATCCCGAAGATCTGCGGATTCCGCCCGCCAACCGGCTGG
AAGCGTTGAAGGGCCAGTGGCGCGGCCAGTGCAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATGGAA
GGCGATGTGCTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10345.95 Da        Isoelectric Point: 6.4654

>AT119457 WP_053503948.1 NZ_CP036255:c5144341-5144051 [Xanthomonas oryzae]
MTVLANIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT119457 NZ_CP036255:c5144341-5144051 [Xanthomonas oryzae]
ATGACAGTCCTAGCCAATATCCACCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGCATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTTGGCCTGCAGGCCGACGACGAACTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References