Detailed information of TA system TA119451

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 4888271..4888857
• Replicon: chromosome
• Accession: NZ_CP036253
• Organism: Xanthomonas oryzae strain NCPPB4346

Toxin (Protein)

• Gene name: graT
• Uniprot ID: -
• Locus tag: EYR26_RS23245
• Protein ID: WP_053503947.1
• Coordinates: 4888579..4888857 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: EYR26_RS23240
• Protein ID: WP_053503948.1
• Coordinates: 4888271..4888561 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EYR26_RS23210	4884565..4884810	-	246	WP_053503950.1	hypothetical protein	-
EYR26_RS23220	4885146..4885478	+	333	WP_003482333.1	hypothetical protein	-
EYR26_RS23230	4885928..4887322	-	1395	WP_053503949.1	nucleoside hydrolase	-
EYR26_RS23240	4888271..4888561	-	291	WP_053503948.1	HigA family addiction module antidote protein	Antitoxin
EYR26_RS23245	4888579..4888857	-	279	WP_053503947.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EYR26_RS23250	4888955..4891216	-	2262	WP_053503946.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (15-92)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10873.52 Da
• Isoelectric Point: 9.3215

>T119451 WP_053503947.1 NZ_CP036253:c4888857-4888579 [Xanthomonas oryzae]
ISSVIDKDAEKIRLSERSRRLPAESQMVARRKLRMLDAAAHPEDLRIPPANRLEALKGQWRGQCSIRINDQWRICFRWME
GDVFQVEIVDYH

Nucleotide

• Length: 279 bp

>T119451 NZ_CP036253:c4888857-4888579 [Xanthomonas oryzae]
ATCAGCAGCGTTATCGACAAGGACGCTGAAAAGATCCGGCTGAGTGAGCGTTCCCGCCGATTGCCGGCCGAGAGTCAGAT
GGTGGCGCGCCGCAAGTTGCGCATGCTCGATGCCGCCGCGCATCCCGAAGATCTGCGGATTCCGCCCGCCAACCGGCTGG
AAGCGTTGAAGGGCCAGTGGCGCGGCCAGTGCAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATGGAA
GGCGATGTGTTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10345.95 Da
• Isoelectric Point: 6.4654

>AT119451 WP_053503948.1 NZ_CP036253:c4888561-4888271 [Xanthomonas oryzae]
MTVLANIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT119451 NZ_CP036253:c4888561-4888271 [Xanthomonas oryzae]
ATGACAGTCCTAGCCAATATCCACCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGCATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTTGGCCTGCAGGCCGATGACGAACTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA