Detailed information of TA system TA119449

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 4842249..4842835
• Replicon: chromosome
• Accession: NZ_CP036252
• Organism: Xanthomonas oryzae strain NJ611

Toxin (Protein)

• Gene name: graT
• Uniprot ID: -
• Locus tag: EYC54_RS22890
• Protein ID: WP_131076070.1
• Coordinates: 4842557..4842835 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: EYC54_RS22885
• Protein ID: WP_053503948.1
• Coordinates: 4842249..4842539 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EYC54_RS22865	4839124..4839456	+	333	WP_003482333.1	hypothetical protein	-
EYC54_RS22875	4839906..4841300	-	1395	WP_131076071.1	nucleoside hydrolase	-
EYC54_RS22885	4842249..4842539	-	291	WP_053503948.1	HigA family addiction module antidote protein	Antitoxin
EYC54_RS22890	4842557..4842835	-	279	WP_131076070.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EYC54_RS22895	4842933..4845194	-	2262	WP_131078921.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (13-92)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10843.50 Da
• Isoelectric Point: 9.3215

>T119449 WP_131076070.1 NZ_CP036252:c4842835-4842557 [Xanthomonas oryzae]
ISSVIDKDAEKIRLGERSRRLPAESQMVARRKLRMLDAAAHPEDLRIPPANRLEALKGQWRGQCSIRINDQWRICFRWME
GDVFQVEIVDYH

Nucleotide

• Length: 279 bp

>T119449 NZ_CP036252:c4842835-4842557 [Xanthomonas oryzae]
ATCAGCAGCGTTATCGACAAGGACGCTGAAAAGATCCGGCTGGGTGAGCGTTCCCGCCGATTGCCGGCCGAGAGTCAGAT
GGTGGCGCGCCGCAAGTTGCGCATGCTCGATGCCGCCGCGCATCCCGAAGATCTGCGGATTCCGCCCGCCAACCGGCTGG
AAGCGTTGAAGGGCCAGTGGCGCGGCCAGTGCAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATGGAA
GGCGATGTGTTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10345.95 Da
• Isoelectric Point: 6.4654

>AT119449 WP_053503948.1 NZ_CP036252:c4842539-4842249 [Xanthomonas oryzae]
MTVLANIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT119449 NZ_CP036252:c4842539-4842249 [Xanthomonas oryzae]
ATGACAGTCCTAGCCAATATCCACCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGCATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTTGGCCTGCAGGCCGATGACGAACTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA