Detailed information of TA system TA119119

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 2149101..2149801
• Replicon: chromosome
• Accession: NZ_CP035952
• Organism: Pseudomonas sp. SNU WT1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: EXN22_RS09895
• Protein ID: WP_130263883.1
• Coordinates: 2149101..2149397 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: EXN22_RS09900
• Protein ID: WP_130263884.1
• Coordinates: 2149400..2149801 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EXN22_RS09875	2145035..2146213	-	1179	WP_130263879.1	efflux RND transporter periplasmic adaptor subunit	-
EXN22_RS09880	2146441..2146920	+	480	WP_130263880.1	sigma-70 family RNA polymerase sigma factor	-
EXN22_RS09885	2147094..2147579	+	486	WP_130263881.1	histidine kinase	-
EXN22_RS09890	2147675..2148985	+	1311	WP_130263882.1	MFS transporter	-
EXN22_RS09895	2149101..2149397	+	297	WP_130263883.1	type II toxin-antitoxin system MqsR family toxin	Toxin
EXN22_RS09900	2149400..2149801	+	402	WP_130263884.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
EXN22_RS09905	2149865..2151529	-	1665	WP_130263885.1	electron transfer flavoprotein-ubiquinone oxidoreductase	-
EXN22_RS09910	2152074..2152823	+	750	WP_010224703.1	electron transfer flavoprotein subunit beta/FixA family protein	-
EXN22_RS09915	2152824..2153753	+	930	WP_130263886.1	FAD-binding protein	-
EXN22_RS09920	2153868..2154692	+	825	WP_130263887.1	transporter substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (2-97)

Antitoxin

• Antitoxin MqsA (3-131)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10988.68 Da
• Isoelectric Point: 7.3226

>T119119 WP_130263883.1 NZ_CP035952:2149101-2149397 [Pseudomonas sp. SNU WT1]
MEKGTPHCRLSKVRALLEAGRVRSTGSALADAAALGLDFDLMLEVVHALDSRDFHKSMTTQADHRIWQDVYRPSTCFGRV
YLKLTVIDDVPIVSFKEL

Nucleotide

• Length: 297 bp

>T119119 NZ_CP035952:2149101-2149397 [Pseudomonas sp. SNU WT1]
ATGGAGAAAGGCACGCCTCATTGCAGGCTTTCAAAAGTCAGGGCGCTGCTTGAGGCCGGTCGGGTTCGCTCGACAGGCTC
TGCGCTTGCGGATGCTGCAGCGTTGGGCCTGGATTTCGATCTGATGCTTGAGGTGGTTCATGCCCTGGACAGCAGGGATT
TTCACAAGAGCATGACCACGCAGGCGGATCATCGAATCTGGCAAGACGTTTACCGTCCCAGCACCTGCTTCGGGCGGGTC
TACCTGAAACTGACGGTAATCGATGATGTGCCCATCGTTTCCTTCAAGGAGTTGTGA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14593.72 Da
• Isoelectric Point: 7.6347

>AT119119 WP_130263884.1 NZ_CP035952:2149400-2149801 [Pseudomonas sp. SNU WT1]
MKCPVCGAAELVSGTRDLSYTYKGETTRVTDVTGDFCPACDERVLGDLESRRVSAAMLAFNRQVNAATVDPQFIATVRKK
LALDQREAAEIFGGGVNAFSRYENGKTKPPVALVKLLKLLDRHPELFEEVRTA

Nucleotide

• Length: 402 bp

>AT119119 NZ_CP035952:2149400-2149801 [Pseudomonas sp. SNU WT1]
ATGAAATGTCCGGTTTGTGGCGCGGCCGAGTTGGTGAGTGGTACTCGTGACCTGTCGTATACCTACAAGGGTGAGACAAC
ACGGGTGACCGACGTCACTGGAGATTTTTGCCCGGCCTGTGACGAACGGGTGCTCGGCGACCTGGAGTCCCGGCGCGTCA
GTGCAGCCATGCTGGCGTTCAATCGGCAGGTCAATGCGGCGACGGTCGATCCGCAGTTCATTGCCACGGTGCGCAAGAAA
CTGGCGCTCGATCAGCGTGAAGCCGCAGAAATATTCGGCGGTGGGGTCAATGCATTTTCCCGTTACGAAAACGGCAAAAC
CAAGCCTCCTGTGGCCCTGGTCAAATTGCTCAAGCTGCTGGATCGGCACCCCGAGCTGTTCGAAGAAGTCAGGACAGCCT
GA