Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2667418..2667680 Replicon chromosome
Accession NZ_CP035791
Organism Staphylococcus aureus strain 592

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ERW13_RS13780 Protein ID WP_001802298.1
Coordinates 2667418..2667522 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2667517..2667680 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ERW13_RS13755 2664215..2664997 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
ERW13_RS13760 2665065..2665922 + 858 WP_000370927.1 Cof-type HAD-IIB family hydrolase -
ERW13_RS13770 2666580..2666738 - 159 WP_001792784.1 hypothetical protein -
ERW13_RS13780 2667418..2667522 + 105 WP_001802298.1 hypothetical protein Toxin
- 2667517..2667680 - 164 - - Antitoxin
ERW13_RS13785 2667955..2669046 - 1092 WP_000495669.1 hypothetical protein -
ERW13_RS13790 2669312..2670289 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
ERW13_RS13795 2670291..2670611 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ERW13_RS13800 2670763..2671428 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T118521 WP_001802298.1 NZ_CP035791:2667418-2667522 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T118521 NZ_CP035791:2667418-2667522 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT118521 NZ_CP035791:c2667680-2667517 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References