Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1921093..1921277 Replicon chromosome
Accession NZ_CP035671
Organism Staphylococcus aureus strain VB31683

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EWG56_RS09565 Protein ID WP_000482647.1
Coordinates 1921093..1921200 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1921217..1921277 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EWG56_RS09540 1916458..1916931 + 474 WP_000456498.1 GyrI-like domain-containing protein -
EWG56_RS09545 1917054..1918265 - 1212 WP_001191976.1 multidrug effflux MFS transporter -
EWG56_RS09550 1918444..1919103 - 660 WP_000831298.1 membrane protein -
EWG56_RS09555 1919163..1920305 - 1143 WP_001176863.1 glycerate kinase -
EWG56_RS09560 1920573..1920959 + 387 WP_000779356.1 flippase GtxA -
EWG56_RS09565 1921093..1921200 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1921217..1921277 - 61 - - Antitoxin
EWG56_RS09570 1921904..1923667 + 1764 WP_001064812.1 ABC transporter ATP-binding protein/permease -
EWG56_RS09575 1923692..1925425 + 1734 WP_000486501.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T118211 WP_000482647.1 NZ_CP035671:1921093-1921200 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T118211 NZ_CP035671:1921093-1921200 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT118211 NZ_CP035671:c1921277-1921217 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References