Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | symE-agrB/SymE(toxin) |
Location | 5422274..5422686 | Replicon | chromosome |
Accession | NZ_CP035545 | ||
Organism | Escherichia coli strain FSIS11705876 |
Toxin (Protein)
Gene name | symE | Uniprot ID | Q8FA88 |
Locus tag | EB814_RS26905 | Protein ID | WP_000132630.1 |
Coordinates | 5422274..5422615 (-) | Length | 114 a.a. |
Antitoxin (RNA)
Gene name | agrB | ||
Locus tag | - | ||
Coordinates | 5422610..5422686 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EB814_RS27910 | 5417842..5418042 | + | 201 | WP_001310455.1 | hypothetical protein | - |
EB814_RS26885 | 5418285..5419697 | - | 1413 | WP_000199295.1 | PLP-dependent aminotransferase family protein | - |
EB814_RS26890 | 5419874..5420038 | + | 165 | WP_000394274.1 | DUF1127 domain-containing protein | - |
EB814_RS26895 | 5420135..5421016 | + | 882 | WP_001304007.1 | DUF262 domain-containing protein | - |
EB814_RS26900 | 5421064..5422227 | + | 1164 | WP_001304006.1 | DUF1524 domain-containing protein | - |
EB814_RS26905 | 5422274..5422615 | - | 342 | WP_000132630.1 | endoribonuclease SymE | Toxin |
- | 5422610..5422686 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_14 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_15 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_15 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_15 | - | Antitoxin |
- | 5422610..5422686 | + | 77 | NuclAT_15 | - | Antitoxin |
EB814_RS26910 | 5422836..5424590 | - | 1755 | WP_000110082.1 | restriction endonuclease subunit S | - |
EB814_RS26915 | 5424590..5426059 | - | 1470 | WP_001302468.1 | type I restriction-modification system subunit M | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 5411767..5430487 | 18720 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12294.13 Da Isoelectric Point: 8.4982
>T118147 WP_000132630.1 NZ_CP035545:c5422615-5422274 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
Download Length: 342 bp
>T118147 NZ_CP035545:c5422615-5422274 [Escherichia coli]
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
Antitoxin
Download Length: 77 bp
>AT118147 NZ_CP035545:5422610-5422686 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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