117666

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2719289..2719568 Replicon chromosome
Accession NZ_CP035369
Organism Staphylococcus aureus strain LAC

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ERW10_RS14220 Protein ID WP_001802298.1
Coordinates 2719289..2719393 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2719389..2719568 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ERW10_RS14195 2714673..2715455 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
ERW10_RS14200 2715523..2716380 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
ERW10_RS14205 2717085..2717177 - 93 WP_001790138.1 hypothetical protein -
ERW10_RS14210 2717466..2718602 + 1137 WP_000115564.1 SAP domain-containing protein -
ERW10_RS15215 2718645..2719128 + 484 Protein_2625 recombinase family protein -
ERW10_RS14220 2719289..2719393 + 105 WP_001802298.1 hypothetical protein Toxin
- 2719389..2719568 - 180 - - Antitoxin
ERW10_RS14225 2719893..2720984 - 1092 WP_000495671.1 lytic regulatory protein -
ERW10_RS14230 2721250..2722230 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
ERW10_RS14235 2722232..2722552 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ERW10_RS14240 2722704..2723369 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T117666 WP_001802298.1 NZ_CP035369:2719289-2719393 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T117666 NZ_CP035369:2719289-2719393 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT117666 NZ_CP035369:c2719568-2719389 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References