Detailed information of TA system TA117658

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 179937..180119
• Replicon: chromosome
• Accession: NZ_CP035369
• Organism: Staphylococcus aureus strain LAC

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ERW10_RS01170
• Protein ID: WP_001801861.1
• Coordinates: 180024..180119 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	179937..179996 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ERW10_RS01155	179075..179452	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
ERW10_RS01160	179646..179822	+	177	Protein_177	transposase	-
ERW10_RS01165	179800..179901	-	102	WP_001791893.1	hypothetical protein	-
-	179937..179996	+	60	-	-	Antitoxin
ERW10_RS01170	180024..180119	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
ERW10_RS01180	180322..180465	+	144	WP_001549059.1	transposase	-
ERW10_RS01190	181069..181452	+	384	WP_000070811.1	hypothetical protein	-
ERW10_RS01195	181463..181639	+	177	WP_000375476.1	hypothetical protein	-
ERW10_RS01200	181641..181826	+	186	WP_000809857.1	hypothetical protein	-
ERW10_RS01205	181940..182581	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
ERW10_RS01210	182799..183350	-	552	WP_000414205.1	hypothetical protein	-
ERW10_RS01215	183448..183792	-	345	WP_000627551.1	DUF3969 family protein	-
ERW10_RS01220	183833..184459	-	627	Protein_187	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	161417..206145	44728

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T117658 WP_001801861.1 NZ_CP035369:c180119-180024 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T117658 NZ_CP035369:c180119-180024 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT117658 NZ_CP035369:179937-179996 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin