Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2957872..2958380 Replicon chromosome
Accession NZ_CP035319
Organism Rhodococcus sp. ABRD24

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ERC79_RS13005 Protein ID WP_131578743.1
Coordinates 2958120..2958380 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ERC79_RS13000 Protein ID WP_131578741.1
Coordinates 2957872..2958123 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ERC79_RS12970 2953139..2954362 + 1224 WP_131578738.1 phosphoserine transaminase -
ERC79_RS12975 2955009..2955488 + 480 WP_131581085.1 YbjN domain-containing protein -
ERC79_RS12980 2955924..2956169 + 246 WP_131578739.1 hypothetical protein -
ERC79_RS23275 2956214..2956570 + 357 WP_207390314.1 hypothetical protein -
ERC79_RS12990 2956638..2957111 + 474 WP_165497113.1 IS3 family transposase -
ERC79_RS12995 2957171..2957498 + 328 Protein_2567 hypothetical protein -
ERC79_RS13000 2957872..2958123 + 252 WP_131578741.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ERC79_RS13005 2958120..2958380 + 261 WP_131578743.1 Txe/YoeB family addiction module toxin Toxin
ERC79_RS13010 2959055..2960155 - 1101 WP_131578745.1 isocitrate/isopropylmalate dehydrogenase family protein -
ERC79_RS13015 2960152..2963325 - 3174 WP_131581087.1 NAD-glutamate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10492.87 Da        Isoelectric Point: 8.0614

>T117612 WP_131578743.1 NZ_CP035319:2958120-2958380 [Rhodococcus sp. ABRD24]
MKLVWDESAWEDYLWWQTQDRKVMRRINTLIKDIERNGNEGIGKPEPLKHGFHGYWSRRITDEHRLVYKISEDEIRIAAC
RYHYGS

Download         Length: 261 bp

>T117612 NZ_CP035319:2958120-2958380 [Rhodococcus sp. ABRD24]
ATGAAACTGGTCTGGGACGAGAGCGCCTGGGAGGACTACCTCTGGTGGCAGACCCAGGACCGCAAGGTCATGAGGCGGAT
CAACACCCTGATCAAGGACATCGAACGGAACGGGAACGAGGGCATCGGCAAACCCGAACCCCTCAAGCACGGCTTCCACG
GCTACTGGTCGCGTCGGATCACCGACGAACACCGACTCGTGTACAAGATCAGCGAGGACGAGATCCGCATCGCGGCCTGC
CGATACCACTACGGGAGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9322.45 Da        Isoelectric Point: 4.6768

>AT117612 WP_131578741.1 NZ_CP035319:2957872-2958123 [Rhodococcus sp. ABRD24]
VKTMTYSESRAKYAETLNAVTDDREEVVITRAGHEPVVMVALDDYESLKETAYLLRSPENARRLLASIDRLEHGTGAARD
LIE

Download         Length: 252 bp

>AT117612 NZ_CP035319:2957872-2958123 [Rhodococcus sp. ABRD24]
GTGAAGACGATGACCTATTCGGAGTCGCGGGCGAAGTATGCCGAGACCTTGAACGCCGTTACCGACGACCGTGAGGAAGT
GGTGATCACCCGGGCCGGCCATGAGCCGGTGGTGATGGTGGCTCTCGACGACTACGAATCGTTGAAGGAGACGGCGTACC
TGCTCCGGAGCCCGGAGAATGCCCGCCGGCTGCTGGCCTCGATCGATCGGCTCGAGCACGGCACCGGGGCCGCCCGCGAC
CTGATCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References